Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMUR2 | Q9GZQ4 | 5/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.56 |
| ▸ | NMUR1 | Q9HB89 | 4/20 | 0.54 |
| ▸ | NTSR2 | O95665 | 5/20 | 0.53 |
| ▸ | NTSR1 | P30989 | 5/20 | 0.53 |
| ▸ | KDM1A | O60341 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | KDM5A | P29375 | 1/20 | 0.53 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | MC4R | P32245 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31064877 | 0.88 | OPRK1 (0.53) | OPRK1NTSR2NTSR1SORT1OPRM1 | |
| SCHEMBL31130616 | 0.86 | MC4R (0.57) | NTSR2NTSR1SORT1MC4R | |
| SCHEMBL29630545 | 0.85 | SLC6A2 (0.50) | NMUR2NMUR1 | |
| SCHEMBL29714014 | 0.85 | NTSR1 (0.64) | NMUR2NTSR2NTSR1SORT1OPRM1 | |
| SCHEMBL30203894 | 0.85 | NMUR2 (0.54) | NMUR2OPRK1NMUR1NTSR2NTSR1 | |
| SCHEMBL30495628 | 0.84 | OPRD1 (0.61) | NMUR2OPRK1NMUR1OPRM1OPRD1 | |
| SCHEMBL30234090 | 0.84 | NMUR2 (0.55) | NMUR2NMUR1NTSR2NTSR1SORT1 | |
| SCHEMBL30385288 | 0.84 | NTSR1 (0.60) | NMUR2OPRK1NTSR2NTSR1SORT1 | |
| SCHEMBL30560038 | 0.84 | NTSR2 (0.65) | OPRK1NTSR2NTSR1SORT1OPRM1 | |
| SCHEMBL29591867 | 0.84 | SLC6A2 (0.52) | NMUR2NMUR1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192843-A1 | PEPTIDES ABLE TO BIND ANGIOTENSIN-CONVERTING ENZYME 2 (ACE2) AND MEDICAL USES THEREOF | Ospedale Pediatrico Bambino Gesù (IT) | 2023-06-14 | — | — | EP | claimed |
| EP-4192843-A1 | PEPTIDES ABLE TO BIND ANGIOTENSIN-CONVERTING ENZYME 2 (ACE2) AND MEDICAL USES THEREOF | Ospedale Pediatrico Bambino Gesù (IT) | 2023-06-14 | — | — | EP | disclosed |