SCHEMBL30446804

SCHEMBL30446804

OB(O)Oc1ccc(Cl)cc1F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 6/20 0.45
PPARA Q07869 6/20 0.45
MRGPRX4 Q96LA9 3/20 0.40
SLC6A4 P31645 3/20 0.40
SLC6A2 P23975 3/20 0.40
SLC6A3 Q01959 2/20 0.40
KCNH2 Q12809 1/20 0.40
USP30 Q70CQ3 1/20 0.37
LMNA P02545 2/20 0.36
NR1I2 O75469 1/20 0.36
TTR P02766 1/20 0.36
PGR P06401 1/20 0.36
HSP90AA1 P07900 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
MAPT P10636 1/20 0.36
HSPA5 P11021 1/20 0.36
HPGD P15428 1/20 0.36
CBR1 P16152 1/20 0.36
TBXA2R P21731 1/20 0.36
AGTR1 P30556 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2414121 1.00 PPARG (0.45) PPARGPPARAMRGPRX4SLC6A4SLC6A2
SCHEMBL30388199 0.86 PPARG (0.36) PPARGPPARAMRGPRX4SLC6A4SLC6A2
SCHEMBL28391205 0.86 PPARG (0.36) PPARGPPARAMRGPRX4SLC6A4SLC6A2
SCHEMBL1943056 0.79 TTR (0.52) MRGPRX4SLC6A2SLC6A3LMNANR1I2
SCHEMBL30506429 0.79 TTR (0.52) MRGPRX4SLC6A2SLC6A3LMNANR1I2
SCHEMBL2268873 0.79 CES2 (0.39) MAPTHPGDKMT2A
SCHEMBL30523912 0.79 CES2 (0.39) MAPTHPGDKMT2A
SCHEMBL30547980 0.78 TTR (0.55) SLC6A2SLC6A3LMNANR1I2TTR
SCHEMBL31030938 0.78 ESR1 (0.38)
SCHEMBL4489583 0.76 TSHR (0.49) MRGPRX4SLC6A4SLC6A2SLC6A3KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112533914-B Compound and organic light emitting device comprising the same 株式会社LG化学 2025-02-21 CN disclosed
CN-119403806-A TREM2 modulators 穆纳治疗有限公司 2025-02-07 CN disclosed
CN-119384416-A Novel compound and organic light emitting device including the same 株式会社LG化学 2025-01-28 CN disclosed
CN-113906036-B Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2024-10-25 CN disclosed
CN-115135657-B Novel compound and organic light emitting device including the same 株式会社LG化学 2024-10-01 CN disclosed
CN-118360050-A Composition, light-emitting device including the same, and electronic apparatus including the light-emitting device 三星电子株式会社 2024-07-19 CN disclosed
CN-112543764-B Amide compound with BET proteolytic induction effect and medical application thereof 田边三菱制药株式会社 2024-05-10 CN disclosed
CN-117897385-A Compound for degrading Bcl-2 family proteins and application of compound in medicine 西藏海思科制药有限公司 2024-04-16 CN disclosed
CN-113767106-B Oxazaquinazolin-7 (8H) -ones, preparation method and medical application thereof 劲方医药科技(上海)有限公司 2024-02-20 CN disclosed
CN-117186155-A Organic electroluminescent material and device 环球展览公司 2023-12-08 CN disclosed
CN-111868053-B Novel compound and organic light emitting device comprising the same 株式会社LG化学 2023-11-28 CN disclosed
CN-113166165-B Heterocyclic compound and organic light-emitting diode comprising same 株式会社LG化学 2023-11-24 CN disclosed
CN-116917292-A Novel compound and organic light emitting device comprising the same 株式会社LG化学 2023-10-20 CN disclosed
CN-116903663-A Organic electroluminescent material and device 环球展览公司 2023-10-20 CN disclosed
CN-116568680-A Organic molecules for optoelectronic devices 三星显示有限公司 2023-08-08 CN disclosed
CN-116568683-A Dibenzofive-membered ring compound and organic electroluminescent device comprising same 株式会社乐普拓 2023-08-08 CN disclosed
CN-112334474-B Compound and organic light emitting device comprising the same 株式会社LG化学 2023-07-21 CN disclosed
CN-116157395-A Luminescent triazine derivatives for optoelectronic devices 三星显示有限公司 2023-05-23 CN disclosed