Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30594439 | 1.00 | TSHR (0.49) | TSHRHTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL27668344 | 0.84 | CYP3A4 (0.42) | TSHRHTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL1943056 | 0.79 | TTR (0.52) | TSHRTP53LMNAHPGDSLC6A2 | |
| SCHEMBL30506429 | 0.79 | TTR (0.52) | TSHRTP53LMNAHPGDSLC6A2 | |
| SCHEMBL29603559 | 0.79 | TP53 (0.43) | TP53CYP3A4ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL457238 | 0.79 | TP53 (0.43) | TP53CYP3A4ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3106476 | 0.79 | TSHR (0.45) | TSHRHTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL6659315 | 0.78 | TRPV4 (0.44) | TP53ALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL30405310 | 0.78 | TRPV4 (0.44) | TP53ALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL30567191 | 0.78 | HTR3E (0.45) | KDM4ETP53ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12289988-B2 | Nitrogen-containing compounds, electronic elements and electronic devices | SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) | 2025-04-29 | — | — | US | disclosed |
| US-20220416164-A1 | NITROGEN-CONTAINING COMPOUNDS, ELECTRONIC ELEMENTS AND ELECTRONIC DEVICES | SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) | 2022-12-29 | — | — | US | disclosed |
| CN-107925001-A | hole transport material | E.I.内穆尔杜邦公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-102292316-A | Glucagon antagonists | — | 2011-12-21 | — | — | CN | disclosed |
| CN-101743224-A | 7-substituted indole mcl-1 inhibitors | ABBOTT LAB | 2010-06-16 | — | — | CN | disclosed |
| US-7592358-B2 | Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-22 | — | — | US | disclosed |
| US-20050234101-A1 | Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12289988-B2 | Nitrogen-containing compounds, electronic elements and electronic devices | NPPA, NES, INA | TSHR 4313/4885HTR2A 2890/4885HTR2C 3343/4885 |
| US-20220416164-A1 | NITROGEN-CONTAINING COMPOUNDS, ELECTRONIC ELEMENTS AND ELECTRONIC DEVICES | NPPA, NES, INA | TSHR 4313/4885HTR2A 2890/4885HTR2C 3343/4885 |
| US-20050234101-A1 | Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds | MCHR1, GPR119, MCHR2 | TSHR 115/4885HTR2A 161/4885HTR2C 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.