SCHEMBL2268873

SCHEMBL2268873

OB(O)Oc1ccc(F)cc1F

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
HSPB1 P04792 3/20 0.39
CA3 P07451 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TRPA1 O75762 4/20 0.38
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
IDO1 P14902 1/20 0.35
AGXT P21549 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30523912 1.00 CES2 (0.39) CES2CES1HSPB1CA3CA6
SCHEMBL1484426 0.84 IDO1 (0.43) CES2CES1HSPB1CA3CA6
SCHEMBL28541327 0.83 HSPB1 (0.37) CES2CES1HSPB1CA3CA6
SCHEMBL3269792 0.83 HSPB1 (0.37) CES2CES1HSPB1CA3CA6
SCHEMBL4087411 0.83 CA3 (0.43) CES2CES1CA3CA6CA5A
SCHEMBL30300590 0.83 CA3 (0.43) CES2CES1CA3CA6CA5A
SCHEMBL31030938 0.81 ESR1 (0.38)
SCHEMBL31114606 0.81 CA3 (0.46) CA3CA6CA5ACA9CA14
SCHEMBL31055822 0.80 ESR2 (0.49)
SCHEMBL2414121 0.79 PPARG (0.45) MAPTHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118336009-A Phenylboronic acid-based additive and electrolyte for lithium/carbon fluoride primary battery 上海大学 2024-07-12 CN claimed
CN-114262330-B Fascaplysin derivative, preparation method and application thereof in resisting MRSA 宁波大学 2023-12-12 CN claimed
EP-1506176-B1 AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM PFIZER ITALIA SRL (IT) 2013-04-24 EP claimed
US-20260015341-A1 PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF HINOVA PHARMACEUTICALS INC (CN) 2026-01-15 US disclosed
EP-4553075-A1 PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Hinova Pharmaceuticals Inc. (CN) 2025-05-14 EP disclosed
WO-2024199444-A1 HETEROAROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海翊维康医药有限责任公司 2024-10-03 WO disclosed
CN-118336009-A Phenylboronic acid-based additive and electrolyte for lithium/carbon fluoride primary battery 上海大学 2024-07-12 CN disclosed
CN-118271331-A Gelsemin derivatives, synthesis method and application thereof in inhibiting tumor cell proliferation 赣江中药创新中心 2024-07-02 CN disclosed
CN-114262330-B Fascaplysin derivative, preparation method and application thereof in resisting MRSA 宁波大学 2023-12-12 CN disclosed
CN-116761834-A Storage stable epoxy resin composition 澳泽化学特罗斯特贝格有限公司 2023-09-15 CN disclosed
CN-114207024-B Storage stable epoxy resin composition 澳泽化学特罗斯特贝格有限公司 2023-08-22 CN disclosed
US-20030080342-A1 Light-emitting element and novel iridium complexes FUJI PHOTO FILM CO., LTD. 2003-05-01 US disclosed
EP-0675118-B1 Biphenylderivatives, process for their preparation and their use as medicaments EISAI CO LTD (JP) 2002-10-09 EP disclosed
US-6455720-B1 AS CATALYSTS TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-09-24 US disclosed
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-05-16 US disclosed
WO-2002036639-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-05-10 WO disclosed
EP-1167372-A1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst Takasago International Corporation (JP) 2002-01-02 EP disclosed
US-6281214-B1 USEFUL FOR TREATING AND AMELIORATING MENTAL DISORDERS EISAI CO., LTD (JP) 2001-08-28 US disclosed
EP-0675118-A2 Biphenylderivatives, process for their preparation and their use as medicaments Eisai Co., Ltd. (JP) 1995-10-04 EP disclosed
EP-0189799-A1 Process for separating cesium ions from aqueous solutions KERNFORSCHUNGSZENTRUM KARLSRUHE GMBH (DE) 1986-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst DDT, PDCD11, PLD2 CES2 3946/4885CES1 3736/4885HSPB1 4793/4885
US-20260015341-A1 PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF PIK3CA, PIK3R4, PIK3R1 CES2 1448/4885CES1 97/4885HSPB1 3412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.