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Melectin

Melectin

SCHEMBL30448502

CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(N)=O)C(C)C)C(C)C

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 14/20 0.62
▸ TFPI P10646 3/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30364495 0.90 TFPI (0.68) RENTFPI
SCHEMBL29358935 0.87 TFPI (0.64) RENTFPI
SCHEMBL31418387 0.86 TFPI (0.63) RENTFPI
SCHEMBL29614957 0.86 TFPI (0.63) TFPI
SCHEMBL30872190 0.83 CXCR4 (0.64) TFPI
SCHEMBL30300729 0.83 REN (0.63) REN
SCHEMBL29401001 0.82 PTH1R (0.68) —
SCHEMBL30711673 0.82 PTH1R (0.68) —
SCHEMBL31332217 0.82 PTH1R (0.66) —
SCHEMBL29557813 0.82 PTH1R (0.57) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4680629-A1 STAPLED PEPTIDES The Florey Institute Of Neuroscience And Mental Health (AU) 2026-01-21 — — EP disclosed
WO-2024187241-A1 STAPLED PEPTIDES THE FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH (AU) 2024-09-19 — — WO disclosed
EP-3423075-B1 STAPLED INTRACELLULAR-TARGETING ANTIMICROBIAL PEPTIDES TO TREAT INFECTION DANA FARBER CANCER INST INC (US) 2024-04-03 — — EP disclosed
CN-113801198-B Hybrid antibacterial peptide and preparation method and application thereof 江苏尚宝牧业有限公司 2023-06-27 — — CN disclosed
CN-113801198-B Hybrid antibacterial peptide and preparation method and application thereof 江苏尚宝牧业有限公司 2023-06-27 — — CN disclosed
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