SCHEMBL29614957

SCHEMBL29614957

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)CN)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(N)=O

nearest known ligand 0.63

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 4/20 0.63
▸ RAMP3 O60896 8/20 0.62
▸ CALCR P30988 8/20 0.62
▸ NPY2R P49146 7/20 0.61
▸ NPY4R P50391 7/20 0.61
▸ NPY5R Q15761 7/20 0.61
▸ NPY1R P25929 5/20 0.61
▸ CXCR4 P61073 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30364495 0.97 TFPI (0.68) TFPIRAMP3CALCRNPY2RNPY4R
SCHEMBL30872190 0.96 CXCR4 (0.64) TFPIRAMP3CALCRNPY2RNPY4R
SCHEMBL31418387 0.92 TFPI (0.63) TFPIRAMP3CALCRNPY2RNPY4R
SCHEMBL29615082 0.88 CALCR (0.61) RAMP3CALCRNPY2RNPY4RNPY5R
Melectin SCHEMBL30448502 0.86 REN (0.62) TFPI
SCHEMBL29358935 0.84 TFPI (0.64) TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL30422242 0.83 CALCR (0.56) RAMP3CALCR
SCHEMBL29843115 0.82 REN (0.58) —
SCHEMBL30277958 0.82 NPY2R (0.62) RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL29724165 0.81 CXCR4 (0.60) TFPIRAMP3CALCRNPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250288656-A1 APPLICATION OF CAERIN 1.1/1.9 COMBINED WITH ANTI-CD47 ANTIBODY IN PREPARING DRUG FOR TREATING MELANOMA WNL BIOMED TECH PTY. LTD. (AU) 2025-09-18 — — US claimed
US-12377186-B2 Antimicrobial biopolymer compositions, methods of synthesis, and applications of use ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2025-08-05 — — US claimed
CN-118634315-A Application of polypeptide in preparation of anti-porcine reproductive and respiratory syndrome virus products 华中农业大学 2024-09-13 — — CN claimed
WO-2024109339-A1 USE OF CAERIN1.1/1.9 COMBINED WITH ANTI-CD47 ANTIBODY IN PREPARATION OF DRUG FOR TREATMENT OF MELANOMA 中奥生物医药技术(广东)有限公司 2024-05-30 — — WO claimed
CN-114395026-B Broad-spectrum antibacterial peptide constructed based on rational design strategy 福州大学 2023-11-21 — — CN claimed
WO-2023142449-A1 BROAD-SPECTRUM ANTIBACTERIAL PEPTIDE CONSTRUCTED ON BASIS OF RATIONAL DESIGN STRATEGY 福州大学 2023-08-03 — — WO claimed
CN-115969960-A Application of Caerin1.1/1.9 peptide in preparation of drugs for inhibiting/treating bacterial biofilm growth 中奥生物医药技术(广东)有限公司 2023-04-18 — — CN claimed
CN-115957306-A Application of Caerin1.1/1.9 combined anti-CD47 antibody in preparation of drugs for treating melanoma 中奥生物医药技术(广东)有限公司 2023-04-14 — — CN claimed
CN-114395026-A Broad-spectrum antibacterial peptide constructed based on rational design strategy 福州大学 2022-04-26 — — CN claimed
US-20250288656-A1 APPLICATION OF CAERIN 1.1/1.9 COMBINED WITH ANTI-CD47 ANTIBODY IN PREPARING DRUG FOR TREATING MELANOMA WNL BIOMED TECH PTY. LTD. (AU) 2025-09-18 — — US disclosed
US-20250288656-A1 APPLICATION OF CAERIN 1.1/1.9 COMBINED WITH ANTI-CD47 ANTIBODY IN PREPARING DRUG FOR TREATING MELANOMA WNL BIOMED TECH PTY. LTD. (AU) 2025-09-18 — — US disclosed
US-20250288656-A1 APPLICATION OF CAERIN 1.1/1.9 COMBINED WITH ANTI-CD47 ANTIBODY IN PREPARING DRUG FOR TREATING MELANOMA WNL BIOMED TECH PTY. LTD. (AU) 2025-09-18 — — US disclosed
US-12377186-B2 Antimicrobial biopolymer compositions, methods of synthesis, and applications of use ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2025-08-05 — — US disclosed
US-12281205-B2 Modified antibacterial compositions and methods THE UNIVERSITY OF MELBOURNE (AU) 2025-04-22 — — US disclosed
CN-115969960-A Application of Caerin1.1/1.9 peptide in preparation of drugs for inhibiting/treating bacterial biofilm growth 中奥生物医药技术(广东)有限公司 2023-04-18 — — CN disclosed
CN-115957306-A Application of Caerin1.1/1.9 combined anti-CD47 antibody in preparation of drugs for treating melanoma 中奥生物医药技术(广东)有限公司 2023-04-14 — — CN disclosed
CN-115957306-A Application of Caerin1.1/1.9 combined anti-CD47 antibody in preparation of drugs for treating melanoma 中奥生物医药技术(广东)有限公司 2023-04-14 — — CN disclosed
CN-115957306-A Application of Caerin1.1/1.9 combined anti-CD47 antibody in preparation of drugs for treating melanoma 中奥生物医药技术(广东)有限公司 2023-04-14 — — CN disclosed
CN-114395026-A Broad-spectrum antibacterial peptide constructed based on rational design strategy 福州大学 2022-04-26 — — CN disclosed
CN-114395026-A Broad-spectrum antibacterial peptide constructed based on rational design strategy 福州大学 2022-04-26 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12281205-B2 Modified antibacterial compositions and methods TUFM, CLPTM1, MRPL21 TFPI 4134/4885RAMP3 3792/4885CALCR 465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback