SCHEMBL29358935

SCHEMBL29358935

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN)C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(N)=O

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 6/20 0.64
▸ REN P00797 5/20 0.64
▸ NPY2R P49146 7/20 0.61
▸ NPY4R P50391 7/20 0.61
▸ NPY5R Q15761 7/20 0.61
▸ NPY1R P25929 5/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30364495 0.87 TFPI (0.68) TFPIRENNPY2RNPY4RNPY5R
Melectin SCHEMBL30448502 0.87 REN (0.62) TFPIREN
SCHEMBL29542556 0.86 TFPI (0.70) TFPINPY2RNPY4RNPY5RNPY1R
Drosocin SCHEMBL29539177 0.86 NPY2R (0.66) TFPIRENNPY2RNPY4RNPY5R
SCHEMBL29776068 0.86 TFPI (0.65) TFPIRENNPY2RNPY4RNPY5R
SCHEMBL29525763 0.84 KDM1A (0.63) TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL29614957 0.84 TFPI (0.63) TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL29778186 0.84 AGTR2 (0.77) TFPIRENNPY2RNPY4RNPY5R
SCHEMBL31418387 0.84 TFPI (0.63) TFPIRENNPY2RNPY4RNPY5R
SCHEMBL32930844 0.83 AGTR1 (0.70) TFPIRENNPY2RNPY4RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026042043-A1 ANTIMICROBIAL COMPOSITIONS FOR HYGIENE APPLICATIONS ITC LIMITED (IN) 2026-02-26 — — WO claimed
EP-4681776-A2 ANTIMICROBIAL THERAPY The Regents of the University of California (US) 2026-01-21 — — EP claimed
EP-4677075-A2 TARGETING CELLS IN STRESSED GROWING CONDITIONS SNIPR Biome ApS (DK) 2026-01-14 — — EP claimed
US-20250339474-A1 ANTIMICROBIAL THERAPY UNIV CALIFORNIA (US) 2025-11-06 — — US claimed
EP-3291824-B1 ANTIMICROBIAL THERAPY UNIV CALIFORNIA (US) 2025-11-05 — — EP claimed
US-20250243208-A1 BICYCLIC HETEROCYCLES AS MRGPRX2 ANTAGONISTS INCYTE CORPORATION 2025-07-31 — — US claimed
US-20250206734-A1 BICYCLIC HETEROCYCLES AS MRGPRX2 ANTAGONISTS INCYTE CORPORATION 2025-06-26 — — US claimed
US-20250154174-A1 BICYCLIC HETEROCYCLES AS MRGPRX2 ANTAGONISTS INCYTE CORPORATION 2025-05-15 — — US claimed
WO-2025042736-A1 BICYCLIC HETEROCYCLES AS MRGPRX2 ANTAGONISTS INCYTE CORPORATION (US) 2025-02-27 — — WO claimed
WO-2025042730-A1 BICYCLIC HETEROCYCLES AS MRGPRX2 ANTAGONISTS INCYTE CORPORATION (US) 2025-02-27 — — WO claimed
EP-4387638-A1 GENETICALLY MODIFIED BACILLUS SUBTILIS STRAIN AND USE AS A LIVE DELIVERY AND PRODUCTION SYSTEM BiomEdit, LLC (US) 2024-06-26 — — EP claimed
EP-4329834-A1 REGENERATIVE BIOACTIVE SUSPENSION DERIVED FROM FRESHLY DISAGGREGATED TISSUE AND METHODS OF USE IN CLINICAL THERAPIES Avita Medical, Inc. (US) 2024-03-06 — — EP claimed
US-20230355671-A1 Upregulation of Cathelicidin Gene Expression as an Adjuvant to Other Treatments for Diseases THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2023-11-09 — — US claimed
US-20230134704-A1 A METHOD OF TREATING CANCER BY UPREGULATING CATHELICIDIN GENE EXPRESSION AND INFUSING NATURAL KILLER CELLS BARRON ANNELISE E (US) 2023-05-04 — — US claimed
WO-2023049155-A1 GENETICALLY MODIFIED BACILLUS SUBTILIS STRAIN AND USE AS A LIVE DELIVERY AND PRODUCTION SYSTEM BIOMEDIT, LLC (US) 2023-03-30 — — WO claimed
EP-4133115-A1 GENETICALLY REPROGRAMMED MYCOPLASMA BACTERIA AND USES THEREOF Fundació Centre de Regulació Genòmica (ES) 2023-02-15 — — EP claimed
WO-2022231904-A1 REGENERATIVE BIOACTIVE SUSPENSION DERIVED FROM FRESHLY DISAGGREGATED TISSUE AND METHODS OF USE IN CLINICAL THERAPIES AVITA MEDICAL, INC. (US) 2022-11-03 — — WO claimed
US-20220339202-A1 REGENERATIVE BIOACTIVE SUSPENSION DERIVED FROM FRESHLY DISAGGREGATED TISSUE AND METHODS OF USE IN CLINICAL THERAPIES AVITA MEDICAL, INC. 2022-10-27 — — US claimed
CN-107735098-B Antimicrobial therapy 加利福尼亚大学董事会 2022-07-29 — — CN claimed
EP-3943160-A1 AMMONIA OXIDIZING BACTERIA FOR TREATMENT OF ACNE Aobiome LLC (US) 2022-01-26 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250154174-A1 BICYCLIC HETEROCYCLES AS MRGPRX2 ANTAGONISTS MRGPRX2, MRGPRX1, MRGPRX4 TFPI 701/4885REN 1003/4885NPY2R 152/4885
US-20250243208-A1 BICYCLIC HETEROCYCLES AS MRGPRX2 ANTAGONISTS MRGPRX2, MRGPRX1, MRGPRX4 TFPI 701/4885REN 1003/4885NPY2R 152/4885
US-20250206734-A1 BICYCLIC HETEROCYCLES AS MRGPRX2 ANTAGONISTS MRGPRX2, MRGPRX1, MRGPRX4 TFPI 701/4885REN 1003/4885NPY2R 152/4885
US-20250339474-A1 ANTIMICROBIAL THERAPY LCT, HM13, ITCH TFPI 710/4885REN 955/4885NPY2R 2611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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