Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22977449 | 1.00 | MAPT (0.44) | MAPTPTK2JAK2JAK1TYK2 | |
| SCHEMBL11465233 | 0.81 | LMNA (0.41) | PTK2LMNAPOLBALDH1A1KDM4E | |
| SCHEMBL25193541 | 0.79 | LMNA (0.43) | PTK2LMNAPOLBALDH1A1KDM4E | |
| SCHEMBL22958184 | 0.79 | PTK2 (0.42) | PTK2JAK2JAK1TYK2LMNA | |
| SCHEMBL17610582 | 0.79 | LMNA (0.40) | MAPTPTK2LMNAPOLBALDH1A1 | |
| SCHEMBL25193199 | 0.78 | ALDH1A1 (0.41) | PTK2JAK2JAK1TYK2ALDH1A1 | |
| SCHEMBL18888437 | 0.78 | ATR (0.51) | TYK2 | |
| SCHEMBL25190521 | 0.77 | MAPK8 (0.42) | MAPTPTK2JAK2JAK1TYK2 | |
| SCHEMBL13170017 | 0.76 | RAB9A (0.54) | JAK2JAK1TYK2DHODHLMNA | |
| SCHEMBL25191601 | 0.76 | LMNA (0.38) | PTK2LMNAPOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348458-A | Imidazolylpyrimidinylamine compounds as CDK2 inhibitors | 因赛特公司 | 2023-06-27 | — | — | CN | disclosed |