Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | ALKBH3 | Q96Q83 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | KDM4B | O94953 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL199471 | 0.76 | MAPT (1.00) | MAPTALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL1192003 | 0.75 | KDM4E (0.51) | MAPTALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL1259728 | 0.74 | MAPT (0.71) | MAPTALDH1A1KDM4ENPC1MAPK1 | |
| SCHEMBL1260514 | 0.72 | MAPT (0.68) | MAPTALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL1192845 | 0.72 | ALDH1A1 (0.55) | MAPTALDH1A1ALKBH3KDM4ENPC1 | |
| SCHEMBL4296230 | 0.72 | HSD17B10 (0.61) | MAPTALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL1260421 | 0.71 | MAPT (0.67) | MAPTALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL880365 | 0.71 | ALDH1A1 (0.62) | MAPTALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL1193289 | 0.71 | EGLN1 (0.68) | MAPTALDH1A1NPC1LMNAMAPK1 | |
| SCHEMBL9375434 | 0.71 | NOTUM (0.49) | MAPTALDH1A1ALKBH3KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11618744-B2 | Benzoimidazoles as prolyl hydroxylase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2023-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11618744-B2 | Benzoimidazoles as prolyl hydroxylase inhibitors | P4HA1, PAH, EGLN3 | MAPT 2583/4885ALDH1A1 46/4885ALKBH3 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.