Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29032731 | 1.00 | LMNA (0.63) | LMNARAB9APOLBNPC1CYP1A2 | |
| SCHEMBL26703989 | 0.87 | LMNA (0.77) | LMNARAB9APOLBNPC1CYP1A2 | |
| SCHEMBL29032738 | 0.86 | CYP1A2 (0.68) | LMNARAB9APOLBNPC1CYP1A2 | |
| SCHEMBL26704026 | 0.83 | RAB9A (0.63) | LMNARAB9APOLBNPC1CYP1A2 | |
| SCHEMBL26703945 | 0.83 | LMNA (0.63) | LMNARAB9APOLBNPC1CYP1A2 | |
| SCHEMBL26704054 | 0.83 | ADORA2A (0.66) | LMNARAB9APOLBNPC1CYP1A2 | |
| SCHEMBL31396771 | 0.82 | CYP1A2 (0.65) | LMNARAB9APOLBNPC1CYP1A2 | |
| SCHEMBL26704104 | 0.82 | RAB9A (0.61) | LMNARAB9APOLBNPC1CYP1A2 | |
| SCHEMBL26703897 | 0.81 | LMNA (0.67) | LMNARAB9APOLBNPC1CYP1A2 | |
| SCHEMBL26703992 | 0.81 | LMNA (0.67) | LMNARAB9APOLBNPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253686-B | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-11-17 | — | — | CN | disclosed |
| CN-116253686-A | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-06-13 | — | — | CN | disclosed |