Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30452031 | 0.90 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9ALMNAMEN1 | |
| SCHEMBL30451051 | 0.85 | SMN1; SMN2 (0.59) | ERN1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL29032779 | 0.85 | SMN1; SMN2 (0.59) | ERN1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL30451059 | 0.80 | CFD (0.61) | ERN1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL29032748 | 0.80 | LMNA (0.52) | ERN1LMNAMEN1KMT2APOLB | |
| SCHEMBL29032786 | 0.79 | POLB (0.58) | ERN1MEN1KMT2APOLBMAPT | |
| SCHEMBL1927498 | 0.78 | SMN1; SMN2 (0.76) | SMN1; SMN2NPC1RAB9ALMNAKMT2A | |
| SCHEMBL31055456 | 0.76 | SMN1; SMN2 (0.54) | ERN1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL29032803 | 0.76 | NPC1 (0.58) | SMN1; SMN2NPC1RAB9ALMNAMEN1 | |
| SCHEMBL29032738 | 0.76 | CYP1A2 (0.68) | SMN1; SMN2NPC1RAB9ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253686-B | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-11-17 | — | — | CN | disclosed |
| CN-116253686-A | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-06-13 | — | — | CN | disclosed |