Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | ERN1 | O75460 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30451611 | 0.91 | HDAC1 (0.60) | EPHX2NR1H4HDAC1MEN1KMT2A | |
| SCHEMBL29032748 | 0.90 | LMNA (0.52) | CFDEPHX2NR1H4ERN1HDAC1 | |
| SCHEMBL1844567 | 0.85 | APP (0.64) | CFDEPHX2NR1H4ERN1HDAC1 | |
| SCHEMBL30450570 | 0.84 | CFD (0.71) | CFDEPHX2NR1H4ERN1HDAC1 | |
| SCHEMBL29032787 | 0.84 | CFD (0.71) | CFDEPHX2NR1H4ERN1HDAC1 | |
| SCHEMBL29032738 | 0.84 | CYP1A2 (0.68) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL29032786 | 0.81 | POLB (0.58) | ERN1HDAC1MEN1KMT2AHDAC2 | |
| SCHEMBL30451319 | 0.80 | ERN1 (0.52) | ERN1HDAC1MEN1KMT2AHDAC2 | |
| SCHEMBL1083633 | 0.79 | MEN1 (0.77) | MEN1KMT2AHDAC2HDAC8HDAC6 | |
| SCHEMBL12497115 | 0.78 | APP (0.63) | CFDEPHX2NR1H4ERN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253686-B | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-11-17 | — | — | CN | disclosed |
| CN-116253686-A | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-06-13 | — | — | CN | disclosed |