Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25244529 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL24252913 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL29684781 | 0.95 | KDM4E (0.60) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL8399454 | 0.89 | KDM4E (0.52) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL16555251 | 0.81 | SLC6A4 (0.49) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL30148118 | 0.81 | L3MBTL1 (0.51) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL14870995 | 0.81 | L3MBTL1 (0.51) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL22498464 | 0.81 | ALDH1A1 (0.52) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL1371009 | 0.80 | KDM4E (0.51) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL14345658 | 0.79 | HTR2C (0.52) | KDM4EALDH1A1MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
| EP-4185592-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | Annexon, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |