Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.37 |
| ▸ | ADH1C | P00326 | 1/20 | 0.37 |
| ▸ | ADH1A | P07327 | 1/20 | 0.37 |
| ▸ | ADH4 | P08319 | 1/20 | 0.37 |
| ▸ | ADH7 | P40394 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | FDPS | P14324 | 3/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3042548 | 0.98 | ACE2 (0.41) | ACE2MAPTADH1BADH1CADH1A | |
| SCHEMBL385558 | 0.92 | CYP3A4 (0.34) | ACE2OPRM1FDPSCA1LMNA | |
| SCHEMBL103020 | 0.83 | — | — | |
| SCHEMBL3034934 | 0.82 | ACE2 (0.47) | ACE2MAPTADH1BADH1CADH1A | |
| SCHEMBL7209537 | 0.82 | LMNA (0.45) | MAPTADH1BADH1CADH1AADH4 | |
| SCHEMBL7204580 | 0.82 | LMNA (0.45) | MAPTADH1BADH1CADH1AADH4 | |
| SCHEMBL7205358 | 0.82 | LMNA (0.45) | MAPTADH1BADH1CADH1AADH4 | |
| SCHEMBL3038480 | 0.81 | LMNA (0.50) | LMNA | |
| SCHEMBL3024811 | 0.80 | ACE2 (0.44) | ACE2MAPTADH1BADH1CADH1A | |
| SCHEMBL8634225 | 0.79 | LMNA (0.41) | MAPTOPRM1SMPD1GPR84FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216736-A2 | 2'-CYANOPYRIMIDINE NUCLEOSIDE COMPOUND | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2010-08-26 | — | — | US | disclosed |
| US-20100056466-A1 | 2'-Cyanopyrimidine Nucleoside Compound | MATSUDA, AKIRA (JP) | 2010-03-04 | — | — | US | disclosed |
| US-6670307-B2 | Such as 2-(2,6-difluorophenyl)-4-(4-(2-ethoxypyridin-5-yl) phenyl)oxazoline; for administration to livestock | HOECHST SCHERING AGREVO GMBH (DE) | 2003-12-30 | — | — | US | disclosed |
| EP-1087967-B1 | 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2003-10-22 | — | — | EP | disclosed |
| US-20030119806-A1 | Azetidine derivatives, processes for their preparation and their use as pesticides | BAYER CROPSCIENCE S.A. (FR) | 2003-06-26 | — | — | US | disclosed |
| WO-2003022808-A1 | AZETIDIN DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE S. A. (FR) | 2003-03-20 | — | — | WO | disclosed |
| US-20020068828-A1 | 1,3-oxazoline and 1,3-thiazoline derivatives, their preparation, and their use as pesticides | BAYER CROPSCIENCE AG (DE) | 2002-06-06 | — | — | US | disclosed |
| US-6300333-B1 | COMPOUNDS AS FUNGICIDES, MITICIDES OR INSECTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-10-09 | — | — | US | disclosed |
| US-6265350-B1 | CONTROLLING HARMFUL FUNGI, INSECTS, ACARINA, MOLLUSKS AND NEMATODES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-07-24 | — | — | US | disclosed |
| EP-1087967-A1 | 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES | Aventis CropScience GmbH (DE) | 2001-04-04 | — | — | EP | disclosed |
| EP-1068197-A1 | SUBSTITUTED PIPERIDINES, METHOD FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES AND FUNGICIDES | Aventis CropScience GmbH (DE) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999065901-A1 | 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 1999-12-23 | — | — | WO | disclosed |
| WO-1999051589-A1 | SUBSTITUTED PIPERIDINES, METHOD FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES AND FUNGICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 1999-10-14 | — | — | WO | disclosed |
| US-5723492-A | LTA4 hydrolase inhibitor pharmaceutical compositions and methods of use | G.D. SEARLE & CO. (US) | 1998-03-03 | — | — | US | disclosed |
| US-5719306-A | ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119806-A1 | Azetidine derivatives, processes for their preparation and their use as pesticides | DDT, CHRM1, CNTN1 | ACE2 2386/4885MAPT 4805/4885ADH1B 2270/4885 |
| US-20100216736-A2 | 2'-CYANOPYRIMIDINE NUCLEOSIDE COMPOUND | NUDT1, DPYD, SLC29A1 | ACE2 1401/4885MAPT 4699/4885ADH1B 1955/4885 |
| US-20020068828-A1 | 1,3-oxazoline and 1,3-thiazoline derivatives, their preparation, and their use as pesticides | MT-CO1, OXA1L, MT-CO3 | ACE2 1397/4885MAPT 3869/4885ADH1B 2795/4885 |
| US-20100056466-A1 | 2'-Cyanopyrimidine Nucleoside Compound | NUDT1, DPYD, SLC29A1 | ACE2 1401/4885MAPT 4699/4885ADH1B 1955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.