Sugi Predict

Sugi Predict / Compounds / Formic Acid

Formic Acid

Formic Acid

SCHEMBL30451490

Cc1nnc(N)c2ccc(-c3cc(B(O)O)cc(F)c3C#N)cc12.O=CO

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.33
▸ HPGD P15428 6/20 0.33
▸ MAPT P10636 3/20 0.33
▸ PKM P14618 3/20 0.33
▸ ATM Q13315 2/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ ALOX12 P18054 2/20 0.33
▸ HTT P42858 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ PRKACA P17612 1/20 0.33
▸ PRKACG P22612 1/20 0.33
▸ PRKACB P22694 1/20 0.33
▸ IL4 P05112 1/20 0.33
▸ KDM4E B2RXH2 6/20 0.32
▸ TDP1 Q9NUW8 2/20 0.32
▸ GAA P10253 3/20 0.31
▸ ABL1 P00519 1/20 0.31
▸ GLA P06280 1/20 0.31
▸ KDR P35968 2/20 0.31
▸ NPSR1 Q6W5P4 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL25244754 1.00 ALDH1A1 (0.33) ALDH1A1HPGDMAPTPKMATM
SCHEMBL24252656 0.95 IL4 (0.35) ALDH1A1HPGDMAPTPKMATM
SCHEMBL25244753 0.89 KDM4E (0.33) ALDH1A1HPGDMAPTPKMATM
SCHEMBL26771118 0.88 IL4 (0.35) ALDH1A1HPGDMAPTPKMATM
Formic Acid SCHEMBL30467607 0.83 PDGFRB (0.36) KDRPDGFRB
Formic Acid SCHEMBL25268266 0.79 MAP4K4 (0.34) ABL1
Formic Acid SCHEMBL30451900 0.79 MAP4K4 (0.34) ABL1
SCHEMBL24252506 0.78 MAP4K4 (0.37) PRKACAPRKACGPRKACBKDRPDGFRB
SCHEMBL24252685 0.77 PDGFRB (0.32) KDRPDGFRB
SCHEMBL24252366 0.77 ABL1 (0.33) ALDH1A1HPGDABL1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070932-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF ANNEXON INC (US) 2026-03-12 — — US disclosed
US-12509474-B2 Inhibitors of complement factors and uses thereof ANNEXON, INC. (US) 2025-12-30 — — US disclosed
US-20240109920-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF ANNEXON, INC. 2024-04-04 — — US disclosed
US-11814404-B2 Inhibitors of complement factors and uses thereof ANNEXON, INC. (US) 2023-11-14 — — US disclosed
CN-116947903-A Inhibitors of complement factors and uses thereof 安尼艾克松股份有限公司 2023-10-27 — — CN disclosed
CN-116261564-A Inhibitors of complement factors and uses thereof 安尼艾克松股份有限公司 2023-06-13 — — CN disclosed
EP-4185592-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF Annexon, Inc. (US) 2023-05-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240109920-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF CFB, CFH, C9 ALDH1A1 653/4885HPGD 823/4885MAPT 1152/4885
US-11814404-B2 Inhibitors of complement factors and uses thereof CFB, CFH, C9 ALDH1A1 653/4885HPGD 823/4885MAPT 1152/4885
US-12509474-B2 Inhibitors of complement factors and uses thereof SSB, UACA, CFH ALDH1A1 3178/4885HPGD 3187/4885MAPT 4803/4885
US-20260070932-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF CFH, CFB, C5 ALDH1A1 3094/4885HPGD 2103/4885MAPT 4737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.