Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | AGPAT2 | O15120 | 4/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL601322 | 0.78 | NOS1 (0.56) | ALDH1A1HSD17B10USP2NPSR1TDP1 | |
| SCHEMBL7202311 | 0.77 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL30451992 | 0.74 | ABL1 (0.46) | ABL1KDM4EALDH1A1HPGDAGPAT2 | |
| SCHEMBL24252484 | 0.74 | ABL1 (0.46) | ABL1KDM4EALDH1A1HPGDAGPAT2 | |
| SCHEMBL1009542 | 0.71 | HSD17B10 (0.51) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL30777062 | 0.71 | FGFR1 (0.47) | KDM4EALDH1A1HSD17B10TDP1 | |
| SCHEMBL27172619 | 0.71 | FGFR1 (0.47) | KDM4EALDH1A1HSD17B10TDP1 | |
| SCHEMBL3977212 | 0.71 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL24252955 | 0.70 | ABL1 (0.52) | ABL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30451948 | 0.70 | ABL1 (0.52) | ABL1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |