SCHEMBL601322

SCHEMBL601322

O=c1[nH]ncc2cc(Cl)ccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.56
ALDH1A1 P00352 2/20 0.56
PARP1 P09874 2/20 0.56
PRKCI P41743 1/20 0.56
PDE4B Q07343 1/20 0.56
HSD17B10 Q99714 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
DYRK1A Q13627 1/20 0.52
MAT2A P31153 1/20 0.46
DAO P14920 2/20 0.43
TYMS P04818 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
USP2 O75604 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
LIG1 P18858 1/20 0.40
IDH1 O75874 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26427164 0.85 PARP1 (0.56) NOS1ALDH1A1PARP1PRKCIPDE4B
SCHEMBL10508282 0.82 ALDH1A1 (0.46) NOS1ALDH1A1PARP1PRKCIPDE4B
SCHEMBL10508284 0.82 ALDH1A1 (0.46) NOS1ALDH1A1PARP1PRKCIPDE4B
SCHEMBL10507388 0.82 ALDH1A1 (0.46) NOS1ALDH1A1PARP1PRKCIPDE4B
SCHEMBL5485566 0.82 ALDH1A1 (0.47) NOS1ALDH1A1PARP1PRKCIPDE4B
SCHEMBL5399593 0.82 HSD17B10 (0.47) NOS1ALDH1A1PARP1PRKCIPDE4B
SCHEMBL7202311 0.80 ALDH1A1 (0.40) NOS1ALDH1A1PARP1PRKCIPDE4B
SCHEMBL7976306 0.78 ALDH1A1 (0.49) NOS1ALDH1A1PARP1PRKCIPDE4B
SCHEMBL30451534 0.78 ABL1 (0.45) ALDH1A1HSD17B10TDP1USP2NPSR1
SCHEMBL25184048 0.78 ALDH1A1 (0.56) NOS1ALDH1A1PARP1PRKCIPDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4207112-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1980-06-10 US claimed
US-4096143-A Process for producing phthalazinone and derivatives of the same FUJI PHOTO FILM CO., LTD. (JA) 1978-06-20 US claimed
US-6423486-B1 None US disclosed
US-20250145592-A1 COMPOUNDS, COMPOSITIONS, AND METHODS TENVIE THERAPEUTICS, INC. 2025-05-08 US disclosed
EP-4479054-A1 COMPOUNDS, COMPOSITIONS, AND METHODS Nico Therapeutics, Inc. (US) 2024-12-25 EP disclosed
US-20240398783-A1 Compounds and Pharmaceutical Compositions Comprising Inhibitors of Amyloid Peptide Interactions with Glycosaminoglycans, Methods of Treatment and Use Thereof GISMO THERAPEUTICS, INC. 2024-12-05 US disclosed
US-20240239757-A1 PHTHALAZINONE DERIVATES AS NLRP3 INFLAMMASOME INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2024-07-18 US disclosed
US-20240239757-A1 PHTHALAZINONE DERIVATES AS NLRP3 INFLAMMASOME INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2024-07-18 US disclosed
EP-4398902-A1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF AMYLOID PEPTIDE INTERACTIONS WITH GLYCOSAMINOGLYCANS, METHODS OF TREATMENT, AND USE THEREOF Gismo Therapeutics, Inc. (US) 2024-07-17 EP disclosed
CN-117999075-A Compounds and pharmaceutical compositions comprising inhibitors of amyloid peptide interaction with glycosaminoglycans, methods of treatment, and uses thereof 吉斯莫治疗股份有限公司 2024-05-07 CN disclosed
WO-2023158708-A1 COMPOUNDS, COMPOSITIONS, AND METHODS DENALI THERAPEUTICS INC. (US) 2023-08-24 WO disclosed
US-4923792-A BENZYLIDENE LEUCO COMPOUNDS AS COLOR-GENERATING REDUCING AGENTS, TOPCOAT OF POLYVINYL ALCOHOL MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-05-08 US disclosed
US-4883747-A LIGHT SENSITIVE SILVER HALIDE, ORGANIC ACID SILVER SALT, LEUCO DYE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-11-28 US disclosed
EP-0294099-A2 Colour photothermographic elements MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-12-07 EP disclosed
US-4237215-A DECOMPOSING N-HALO COMPOUND IN PRESENCE OF ORGANIC SILVER SALT TO PRODUCE SILVER HALIDE FUJI PHOTO FILM CO., LTD. (JP) 1980-12-02 US disclosed
US-4207112-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1980-06-10 US disclosed
US-4144072-A CONTAINING A PHTHALAZINONE AND A PHTHALIMIDE FUJI PHOTO FILM CO., LTD. (JP) 1979-03-13 US disclosed
US-4125403-A ORGANIC SILVER SALT, SILVER HALIDE, REDUCING AGENT, PHTHALAZINONE, AND A BENZOXAZINEDIONE OR QUINAZOLINEDIONE FUJI PHOTO FILM CO., LTD. 1978-11-14 US disclosed
US-4096143-A Process for producing phthalazinone and derivatives of the same FUJI PHOTO FILM CO., LTD. (JA) 1978-06-20 US disclosed
US-4076534-A Heat developable light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240398783-A1 Compounds and Pharmaceutical Compositions Comprising Inhibitors of Amyloid Peptide Interactions with Glycosaminoglycans, Methods of Treatment and Use Thereof PRNP, GBA1, GBA3 NOS1 2825/4885ALDH1A1 3486/4885PARP1 3487/4885
US-20240239757-A1 PHTHALAZINONE DERIVATES AS NLRP3 INFLAMMASOME INHIBITORS NLRP3, NLRP1, PYCARD NOS1 1427/4885ALDH1A1 1522/4885PARP1 499/4885
US-20250145592-A1 COMPOUNDS, COMPOSITIONS, AND METHODS NLRP3, NLRP1, NOD1 NOS1 1744/4885ALDH1A1 4174/4885PARP1 1670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.