Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.59 |
| ▸ | WNT3A | P56704 | 1/20 | 0.59 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | TYK2 | P29597 | 1/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450640 | 0.87 | KDM4E (0.60) | CTNNB1WNT3AGRM4RAB9ANPC1 | |
| SCHEMBL4508472 | 0.84 | CES2 (0.64) | GRM4RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL28727383 | 0.82 | CES2 (0.61) | GRM4RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL3140037 | 0.82 | HPGD (0.64) | RAB9ANPC1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL27178209 | 0.81 | NPC1 (0.74) | RAB9ANPC1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL27178215 | 0.81 | NPC1 (0.74) | RAB9ANPC1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL13161971 | 0.80 | CTNNB1 (0.66) | CTNNB1WNT3AGRM4RAB9ANPC1 | |
| SCHEMBL8597610 | 0.79 | LMNA (0.61) | RAB9ANPC1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL3188677 | 0.78 | ALDH1A1 (0.62) | RAB9ANPC1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL29531380 | 0.77 | NPC1 (0.79) | GRM4RAB9ANPC1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261562-A | PI 3K-alpha inhibitors and methods of use thereof | 传达治疗有限公司 | 2023-06-13 | — | — | CN | disclosed |