SCHEMBL30451695

SCHEMBL30451695

COc1ccc(-c2cccc(-c3occ([SiH3])c3-c3ccco3)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 2/20 0.48
ABCB1 P08183 2/20 0.48
BCR P11274 2/20 0.48
ALDH1A1 P00352 5/20 0.41
KDM4E B2RXH2 4/20 0.41
HPGD P15428 4/20 0.41
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYP1A1 P04798 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2E1 P05181 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C8 P10632 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2A6 P11509 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP4B1 P13584 1/20 0.39
CYP2B6 P20813 1/20 0.39
CYP3A5 P20815 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29213005 0.74 PIN1 (0.45) ABL1ABCB1BCRALDH1A1KDM4E
SCHEMBL3685934 0.70 TAAR1 (0.55) ALDH1A1KDM4EHPGDRAB9ANPC1
SCHEMBL29213065 0.70 PIN1 (0.40) ABL1ABCB1BCRALDH1A1KDM4E
SCHEMBL1180429 0.70 ABL1 (0.83) ABL1ABCB1BCRHPGDRAB9A
SCHEMBL1181204 0.68 ABL1 (0.81) ABL1ABCB1BCRCYP1A1CYP1A2
SCHEMBL2045217 0.67 ALDH1A1 (0.67) ALDH1A1KDM4EHPGDRAB9ANPC1
SCHEMBL1180412 0.67 ABL1 (0.77) ABL1ABCB1BCRCYP1A1CYP1A2
SCHEMBL792197 0.67 ABL1 (0.77) ABL1ABCB1BCRCYP1A1CYP1A2
SCHEMBL27649742 0.67 ABL1 (0.77) ABL1ABCB1BCRALDH1A1KDM4E
SCHEMBL27399871 0.65 ABL1 (0.74) ABL1ABCB1BCRHPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115073401-B 2,3 '-bisfuran compound, 2,3' -oligomeric furan compound, and preparation methods and applications thereof 华南理工大学 2023-07-14 CN disclosed