SCHEMBL30451804

SCHEMBL30451804

O=C1OC2(c3ccccc31)c1ccc(O)c(Cl)c1Oc1c(Cl)c(O)c(O)c(O)c12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNG2 P59768 1/20 0.63
GNB1 P62873 1/20 0.63
SMAD3 P84022 2/20 0.52
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
TDP1 Q9NUW8 4/20 0.46
RECQL P46063 2/20 0.46
BLM P54132 2/20 0.46
ACE2 Q9BYF1 2/20 0.46
PRMT1 Q99873 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
USP2 O75604 1/20 0.46
THRB P10828 1/20 0.46
CDK2 P24941 1/20 0.46
CHAT P28329 1/20 0.46
BLVRB P30043 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
MAPT P10636 4/20 0.44
FTO Q9C0B1 2/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL498536 0.89 GNG2 (0.74) GNG2GNB1SMAD3MEN1KMT2A
SCHEMBL29740272 0.89 GNG2 (0.74) GNG2GNB1SMAD3MEN1KMT2A
SCHEMBL30929844 0.86 GNG2 (0.55) GNG2GNB1SMAD3MEN1KMT2A
SCHEMBL3624632 0.85 GNG2 (0.65) GNG2GNB1SMAD3MEN1KMT2A
SCHEMBL31756957 0.81 GNG2 (0.58) GNG2GNB1SMAD3MEN1KMT2A
SCHEMBL29363922 0.81 GNG2 (0.58) GNG2GNB1SMAD3MEN1KMT2A
SCHEMBL20526266 0.78 SMAD3 (0.49) GNG2GNB1SMAD3MEN1KMT2A
SCHEMBL29942282 0.78 GNG2 (1.00) GNG2GNB1SMAD3MEN1KMT2A
SCHEMBL29424349 0.78 GNG2 (1.00) GNG2GNB1SMAD3MEN1KMT2A
SCHEMBL30408346 0.78 GNG2 (1.00) GNG2GNB1SMAD3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119499358-A Self-assembled polypeptide nano-enzyme and application thereof 中国科学院生物物理研究所 2025-02-25 CN disclosed
CN-118846205-A Antioxidant and photodynamic responsive antibacterial hydrogel dressing and preparation and application thereof 重庆医科大学 2024-10-29 CN disclosed