SCHEMBL3624632

SCHEMBL3624632

O=C1OC2(c3ccccc31)c1ccc(O)c(Cl)c1Oc1c2cc(Cl)c(O)c1Cl

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNG2 P59768 1/20 0.65
GNB1 P62873 1/20 0.65
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
TDP1 Q9NUW8 4/20 0.54
RECQL P46063 2/20 0.54
BLM P54132 2/20 0.54
ACE2 Q9BYF1 2/20 0.54
PRMT1 Q99873 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
USP2 O75604 2/20 0.54
THRB P10828 1/20 0.54
CDK2 P24941 1/20 0.54
CHAT P28329 1/20 0.54
BLVRB P30043 1/20 0.54
RXFP1 Q9HBX9 1/20 0.54
MAPT P10636 6/20 0.49
SMAD3 P84022 2/20 0.49
FTO Q9C0B1 2/20 0.49
CYP2C19 P33261 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29486978 0.93 MEN1 (0.61) GNG2GNB1MEN1KMT2ATDP1
SCHEMBL498286 0.93 MEN1 (0.61) GNG2GNB1MEN1KMT2ATDP1
SCHEMBL498536 0.90 GNG2 (0.74) GNG2GNB1MEN1KMT2ATDP1
SCHEMBL29740272 0.90 GNG2 (0.74) GNG2GNB1MEN1KMT2ATDP1
SCHEMBL30451804 0.85 GNG2 (0.63) GNG2GNB1MEN1KMT2ATDP1
SCHEMBL28626002 0.84 FTO (0.70) GNG2GNB1MEN1KMT2ATDP1
SCHEMBL8607854 0.81 FTO (0.73) GNG2GNB1MEN1KMT2ATDP1
SCHEMBL5886188 0.81 MEN1 (0.58) GNG2GNB1MEN1KMT2ATDP1
SCHEMBL3717351 0.80 SMAD3 (0.45) GNG2GNB1MEN1KMT2ATDP1
SCHEMBL30408346 0.80 GNG2 (1.00) GNG2GNB1MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7842826-B2 Process for synthesizing halogenated derivatives of fluorescein for use in the production of non-volatile memory devices STMICROELECTRONICS S.R.L. (IT) 2010-11-30 US claimed
US-20080061289-A1 PROCESS FOR SYNTHESIZING HALOGENATED DERIVATIVES OF FLUORESCEIN FOR USE IN THE PRODUCTION OF NON-VOLATILE MEMORY DEVICES STMICROELECTRONICS S.R.L. (IT) 2008-03-13 US claimed
US-7842826-B2 Process for synthesizing halogenated derivatives of fluorescein for use in the production of non-volatile memory devices STMICROELECTRONICS S.R.L. (IT) 2010-11-30 US disclosed
US-7842826-B2 Process for synthesizing halogenated derivatives of fluorescein for use in the production of non-volatile memory devices STMICROELECTRONICS S.R.L. (IT) 2010-11-30 US disclosed
US-7842826-B2 Process for synthesizing halogenated derivatives of fluorescein for use in the production of non-volatile memory devices STMICROELECTRONICS S.R.L. (IT) 2010-11-30 US disclosed
US-7842826-B2 Process for synthesizing halogenated derivatives of fluorescein for use in the production of non-volatile memory devices STMICROELECTRONICS S.R.L. (IT) 2010-11-30 US disclosed
US-20080061289-A1 PROCESS FOR SYNTHESIZING HALOGENATED DERIVATIVES OF FLUORESCEIN FOR USE IN THE PRODUCTION OF NON-VOLATILE MEMORY DEVICES STMICROELECTRONICS S.R.L. (IT) 2008-03-13 US disclosed
US-20080061289-A1 PROCESS FOR SYNTHESIZING HALOGENATED DERIVATIVES OF FLUORESCEIN FOR USE IN THE PRODUCTION OF NON-VOLATILE MEMORY DEVICES STMICROELECTRONICS S.R.L. (IT) 2008-03-13 US disclosed
US-20080061289-A1 PROCESS FOR SYNTHESIZING HALOGENATED DERIVATIVES OF FLUORESCEIN FOR USE IN THE PRODUCTION OF NON-VOLATILE MEMORY DEVICES STMICROELECTRONICS S.R.L. (IT) 2008-03-13 US disclosed
US-20080061289-A1 PROCESS FOR SYNTHESIZING HALOGENATED DERIVATIVES OF FLUORESCEIN FOR USE IN THE PRODUCTION OF NON-VOLATILE MEMORY DEVICES STMICROELECTRONICS S.R.L. (IT) 2008-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080061289-A1 PROCESS FOR SYNTHESIZING HALOGENATED DERIVATIVES OF FLUORESCEIN FOR USE IN THE PRODUCTION OF NON-VOLATILE MEMORY DEVICES FASTKD5, KCNA5, KCNQ5 GNG2 3802/4885GNB1 3231/4885MEN1 2830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.