SCHEMBL498536

SCHEMBL498536

O=C1OC2(c3ccccc31)c1ccc(O)c(Cl)c1Oc1c2ccc(O)c1Cl

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNG2 P59768 1/20 0.74
GNB1 P62873 1/20 0.74
MAPT P10636 6/20 0.55
MEN1 O00255 5/20 0.55
KMT2A Q03164 5/20 0.55
TDP1 Q9NUW8 4/20 0.55
RECQL P46063 2/20 0.55
BLM P54132 2/20 0.55
PRMT1 Q99873 2/20 0.55
ACE2 Q9BYF1 2/20 0.55
SMAD3 P84022 2/20 0.55
FTO Q9C0B1 2/20 0.55
CYP2C19 P33261 2/20 0.55
HTT P42858 2/20 0.55
HPGD P15428 1/20 0.55
L3MBTL1 Q9Y468 2/20 0.53
USP2 O75604 2/20 0.53
THRB P10828 1/20 0.53
CDK2 P24941 1/20 0.53
CHAT P28329 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29740272 1.00 GNG2 (0.74) GNG2GNB1MAPTMEN1KMT2A
SCHEMBL3624632 0.90 GNG2 (0.65) GNG2GNB1MAPTMEN1KMT2A
SCHEMBL30451804 0.89 GNG2 (0.63) GNG2GNB1MAPTMEN1KMT2A
SCHEMBL8607854 0.88 FTO (0.73) GNG2GNB1MAPTMEN1KMT2A
SCHEMBL29942282 0.85 GNG2 (1.00) GNG2GNB1MAPTMEN1KMT2A
SCHEMBL334144 0.85 GNG2 (1.00) GNG2GNB1MAPTMEN1KMT2A
SCHEMBL29424349 0.85 GNG2 (1.00) GNG2GNB1MAPTMEN1KMT2A
SCHEMBL30408346 0.85 GNG2 (1.00) GNG2GNB1MAPTMEN1KMT2A
SCHEMBL17201722 0.84 GNG2 (0.76) GNG2GNB1MAPTMEN1KMT2A
SCHEMBL3654970 0.83 GNG2 (0.74) GNG2GNB1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
US-20230310285-A1 DEVELOPER COMPOSITION COMPRISING DIRECT DYE L'OREAL (FR) 2023-10-05 US claimed
WO-2023192788-A1 DEVELOPER COMPOSITION COMPRISING DIRECT DYE L'OREAL (FR) 2023-10-05 WO claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
EP-1192450-B1 HIGH ENERGY PHOTOTHERAPEUTIC AGENTS PROVECTUS PHARMATECH INC (US) 2014-12-03 EP claimed
EP-1753467-B1 DIAGNOSTIC AGENTS FOR POSITRON EMISSION IMAGING USING RADIOLABELED HALOGENATED XANTHENES AND METHODS FOR POSITRON EMISSION IMAGING WITH RADIOLABELED HALOGENATED XANTHENE DIAGNOSTIC AGENTS PROVECTUS PHARMATECH INC (US) 2013-01-09 EP claimed
US-7427389-B2 Diagnostic agents for positron emission imaging using radiolabeled halogenated xanthenes PROVECTUS PHARMATECH, INC. (US) 2008-09-23 US claimed
EP-1753467-A4 DIAGNOSTIC AGENTS FOR POSITRON EMISSION IMAGING USING RADIOLABELED HALOGENATED XANTHENES AND METHODS FOR POSITRON EMISSION IMAGING WITH RADIOLABELED HALOGENATED XANTHENE DIAGNOSTIC AGENTS XANTECH PHARMACEUTICALS INC (US) 2008-09-17 EP claimed
EP-1311261-B1 MEDICAMENTS FOR CHEMOTHERAPEUTIC TREATMENT OF DISEASE PHOTOGEN INC (US) 2008-01-23 EP claimed
EP-1292298-B1 INTRACORPOREAL MEDICAMENTS FOR HIGH ENERGY PHOTOTHERAPEUTIC TREATMENT OF DISEASE PHOTOGEN INC (US) 2007-03-28 EP claimed
EP-1292298-A1 INTRACORPOREAL MEDICAMENTS FOR HIGH ENERGY PHOTOTHERAPEUTIC TREATMENT OF DISEASE Photogen, Inc. (US) 2003-03-19 EP claimed
EP-1284727-A1 INTRACORPOREAL MEDICAMENTS FOR PHOTODYNAMIC TREATMENT OF DISEASE Photogen, Inc. (US) 2003-02-26 EP claimed
US-20020161035-A1 Medicaments for chemotherapeutic treatment of disease PHOTOGEN, INC. 2002-10-31 US claimed
EP-1210078-A1 IMPROVED TOPICAL MEDICAMENTS AND METHODS FOR PHOTODYNAMIC TREATMENT OF DISEASE Photogen, Inc. (US) 2002-06-05 EP claimed
WO-2002005812-A1 MEDICAMENTS FOR CHEMOTHERAPEUTIC TREATMENT OF DISEASE PHOTOGEN, INC. (US) 2002-01-24 WO claimed
US-20020001567-A1 Intracorporeal medicaments for high energy phototherapeutic treatment of disease PHOTOGEN, INC. 2002-01-03 US claimed
WO-2001076595-A1 INTRACORPOREAL MEDICAMENTS FOR HIGH ENERGY PHOTOTHERAPEUTIC TREATMENT OF DISEASE PHOTOGEN, INC. (US) 2001-10-18 WO claimed
WO-2001072301-A1 INTRACORPOREAL MEDICAMENTS FOR PHOTODYNAMIC TREATMENT OF DISEASE PHOTOGEN, INC. (US) 2001-10-04 WO claimed
US-20010022970-A1 Intracorporeal medicaments for photodynamic treatment of disease PHOTOGEN, INC. 2001-09-20 US claimed
WO-2001012181-A1 IMPROVED TOPICAL MEDICAMENTS AND METHODS FOR PHOTODYNAMIC TREATMENT OF DISEASE PHOTOGEN, INC. (US) 2001-02-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230310285-A1 DEVELOPER COMPOSITION COMPRISING DIRECT DYE TYR, CYB5R3, POLR1C GNG2 1706/4885GNB1 2112/4885MAPT 3307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.