SCHEMBL30708993

SCHEMBL30708993

N#Cc1ccc(-c2ccc(-c3ccc(-c4ccc(Cl)cc4)c4ccccc34)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.48
MAOB P27338 2/20 0.48
CYP1A2 P05177 1/20 0.45
MMP3 P08254 1/20 0.44
SQOR Q9Y6N5 1/20 0.42
TSHR P16473 2/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
HTT P42858 1/20 0.42
NLRP3 Q96P20 1/20 0.42
MAPKAPK2 P49137 1/20 0.42
ADORA2A P29274 2/20 0.41
ADORA1 P30542 2/20 0.41
GSK3B P49841 1/20 0.41
CYP11B2 P19099 1/20 0.41
KIF11 P52732 2/20 0.40
PDK2 Q15119 1/20 0.40
TDO2 P48775 1/20 0.40
TNKS O95271 1/20 0.40
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23624495 0.98 MAOA (0.50) MAOAMAOBCYP1A2MMP3SQOR
SCHEMBL18322222 0.88 TSHR (0.52) MAOAMAOBMMP3TSHRCYP11B2
SCHEMBL30451858 0.88 TSHR (0.52) MAOAMAOBMMP3TSHRCYP11B2
SCHEMBL23624359 0.85 CYP1A2 (0.48) MAOAMAOBCYP1A2MMP3TSHR
SCHEMBL30709037 0.85 MAOA (0.48) MAOAMAOBCYP1A2MMP3TSHR
SCHEMBL4446050 0.84 MAOA (0.64) MAOAMAOBCYP1A2MMP3TSHR
SCHEMBL23635770 0.83 MAOA (0.50) MAOAMAOBCYP1A2MMP3TSHR
SCHEMBL12295925 0.82 CYP1A2 (0.57) CYP1A2TSHRLMNATNKS
SCHEMBL21416152 0.81 MAOA (0.48) MAOAMAOBCYP1A2MMP3TSHR
SCHEMBL26492407 0.81 GABRA1 (0.49) MAOAMAOBMMP3TSHRCYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116903548-A Compound, composition for organic electroluminescent device, and display device SK株式会社 2023-10-20 CN disclosed