Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29178262 | 0.92 | TRPA1 (0.34) | TRPA1ATMCYP1A2CYP2A6 | |
| SCHEMBL971422 | 0.81 | ACHE (0.43) | CYP1A2CYP2A6TSHRACHECA1 | |
| SCHEMBL29725175 | 0.81 | ACHE (0.43) | CYP1A2CYP2A6TSHRACHECA1 | |
| Hydrochloric Acid SCHEMBL29103124 | 0.75 | ACHE (0.36) | CYP1A2CYP2A6TSHRACHECA1 | |
| SCHEMBL31212632 | 0.74 | ACHE (0.37) | TSHRACHECA1CA2CA9 | |
| Benzene SCHEMBL22829865 | 0.71 | TRPA1 (0.58) | TRPA1ATMCYP1A2CYP2A6TSHR | |
| SCHEMBL18925756 | 0.70 | DRD4 (0.36) | CA1CA2CA9ALDH1A1CA12 | |
| Acetic Acid SCHEMBL29025325 | 0.70 | HPGD (0.36) | ACHECA2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL40704 | 0.68 | — | — | |
| SCHEMBL5494561 | 0.68 | TRPA1 (0.61) | TRPA1ATMCYP1A2CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12571798-B2 | Cancer biomarkers and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-03-10 | — | — | US | disclosed |
| US-12332245-B2 | Cancer biomarkers and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-06-17 | — | — | US | disclosed |
| EP-3796002-B1 | CANCER BIOMARKERS AND METHODS OF USE THEREOF | UNIV CALIFORNIA (US) | 2023-11-22 | — | — | EP | disclosed |
| US-20230204591-A1 | CANCER BIOMARKERS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12571798-B2 | Cancer biomarkers and methods of use thereof | MKI67, BRCA1, CD68 | TRPA1 3966/4885ATM 2941/4885CYP1A2 4742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.