Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.39 |
| ▸ | BRS3 | P32247 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GCG | P01275 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28435954 | 1.00 | HDAC4 (0.40) | HDAC4EGLN1BRS3GCGRMAPT | |
| SCHEMBL28441262 | 0.86 | HDAC4 (0.42) | HDAC4EGLN1GCGRMAPTALDH1A1 | |
| SCHEMBL25875342 | 0.80 | MAPT (0.36) | HDAC4EGLN1GCGRMAPTALDH1A1 | |
| SCHEMBL22534381 | 0.76 | RAB9A (0.49) | EGLN1MAPTKDM4E | |
| SCHEMBL28414160 | 0.73 | EGLN1 (0.46) | EGLN1ALDH1A1RET | |
| SCHEMBL30250133 | 0.73 | EGLN1 (0.46) | EGLN1ALDH1A1RET | |
| SCHEMBL21744565 | 0.72 | EGLN1 (0.44) | EGLN1MAPTALDH1A1KDM4E | |
| SCHEMBL28441796 | 0.72 | EGLN1 (0.44) | EGLN1RET | |
| SCHEMBL17966640 | 0.72 | KCNJ1 (0.56) | EGLN1MAPTALDH1A1KDM4E | |
| SCHEMBL29520978 | 0.72 | KCNJ1 (0.56) | EGLN1MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484479-B | Azacyclic compounds, pharmaceutical compositions containing the same, and methods of making and using the same | 四川科伦博泰生物医药股份有限公司 | 2023-06-13 | — | — | CN | disclosed |