Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2500952 | 1.00 | TSHR (0.49) | TSHRSMN1; SMN2CA2GABRPGABRD | |
| Hydrochloric Acid SCHEMBL17873669 | 0.98 | TSHR (0.47) | TSHRSMN1; SMN2CA2GABRPGABRD | |
| SCHEMBL575044 | 0.82 | GABRP (0.61) | TSHRSMN1; SMN2CA2GABRPGABRD | |
| SCHEMBL10123136 | 0.82 | TSHR (0.50) | TSHRSMN1; SMN2GABRPGABRDGABRA1 | |
| SCHEMBL5709790 | 0.81 | TSHR (0.54) | TSHRSMN1; SMN2ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL7020108 | 0.81 | GABRP (0.59) | TSHRSMN1; SMN2CA2GABRPGABRD | |
| SCHEMBL2827343 | 0.80 | CYP1A2 (0.58) | TSHRSMN1; SMN2GABRPGABRDGABRA1 | |
| SCHEMBL2091577 | 0.80 | TSHR (0.53) | TSHRSMN1; SMN2ADRA2AADRA2BADRA2C | |
| SCHEMBL15120986 | 0.79 | TSHR (0.47) | TSHRSMN1; SMN2GABRPGABRDGABRA1 | |
| SCHEMBL18291273 | 0.78 | GABRP (0.72) | SMN1; SMN2CA2GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129091-A1 | THIENOPYRROLOTRIAZINE COMPOUNDS, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI (FR) | 2025-04-24 | — | — | US | disclosed |
| WO-2024261328-A1 | AMIDE-AMINE COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | AUGUSTINE THERAPEUTICS (BE) | 2024-12-26 | — | — | WO | disclosed |
| US-20240315994-A1 | SMALL MOLECULE MODULATORS OF FERROPTOSIS | ARPEGGIO BIOSCIENCES, INC. | 2024-09-26 | — | — | US | disclosed |
| CN-111484479-B | Azacyclic compounds, pharmaceutical compositions containing the same, and methods of making and using the same | 四川科伦博泰生物医药股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129091-A1 | THIENOPYRROLOTRIAZINE COMPOUNDS, THEIR PREPARATION AND THEIR THERAPEUTIC USE | TPMT, TYMP, TBXA2R | TSHR 360/4885SMN1; SMN2 3719/4885CA2 3131/4885 |
| US-20240315994-A1 | SMALL MOLECULE MODULATORS OF FERROPTOSIS | GPX4, GPX1, AIFM2 | TSHR 2012/4885SMN1; SMN2 3289/4885CA2 2566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.