Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 4/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23879270 | 1.00 | HPGD (0.44) | HPGDLMNAAPEX1JAK1TYK2 | |
| SCHEMBL4324495 | 0.83 | ALDH1A1 (0.47) | HPGDLMNAKMT2AALDH1A1KDM4E | |
| SCHEMBL30452297 | 0.81 | MRGPRX4 (0.49) | HPGDAPEX1ALDH1A1KDM4ENPC1 | |
| SCHEMBL23879261 | 0.81 | MRGPRX4 (0.49) | HPGDAPEX1ALDH1A1KDM4ENPC1 | |
| SCHEMBL23879250 | 0.81 | KMT2A (0.42) | HPGDLMNAKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL4450651 | 0.80 | TSHR (0.50) | HPGDLMNAKMT2AALDH1A1KDM4E | |
| SCHEMBL17207245 | 0.78 | LMNA (0.53) | HPGDLMNAAPEX1JAK1TYK2 | |
| SCHEMBL27747787 | 0.77 | HPGD (0.69) | HPGDLMNAKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9427493 | 0.77 | MAPT (0.43) | HPGDLMNAKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL22059503 | 0.76 | HPGD (0.49) | HPGDLMNAAPEX1JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253404-B | Nitrogen-containing heterocyclic compound and composition, preparation method and application thereof | 上海医药集团股份有限公司 | 2023-05-23 | — | — | CN | disclosed |