Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 3/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 6/20 | 0.35 |
| ▸ | HTR2C | P28335 | 6/20 | 0.35 |
| ▸ | HTR2B | P41595 | 6/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30452566 | 0.81 | GRIN2B (0.40) | NOS2NOS3SIGMAR1 | |
| SCHEMBL30429738 | 0.74 | TRPA1 (0.34) | NOS2NOS3TRPA1 | |
| SCHEMBL5008439 | 0.68 | NOS3 (0.43) | NOS2NOS3TRPA1 | |
| SCHEMBL18464841 | 0.68 | TRPA1 (0.38) | TRPA1 | |
| SCHEMBL31303677 | 0.68 | NOS3 (0.43) | NOS2NOS3TRPA1 | |
| SCHEMBL14953404 | 0.68 | KEAP1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL1509729 | 0.67 | KEAP1 (0.35) | — | |
| SCHEMBL11458329 | 0.66 | PRCP (0.44) | PRCPHTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL14990041 | 0.66 | PLAU (0.44) | PRCPHTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL29949831 | 0.66 | PLAU (0.44) | PRCPHTR2AHTR2CHTR2BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110563631-B | IDO inhibiting compound and application thereof | 爱斯特（成都）生物制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |