Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTR1E | P28566 | 2/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26464123 | 0.88 | TP53 (0.65) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL26464105 | 0.88 | TP53 (0.65) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL28291198 | 0.82 | TP53 (0.52) | MAPTTP53BACE1 | |
| SCHEMBL23099908 | 0.81 | BACE1 (0.47) | ALDH1A1MAPTMEN1KMT2ABACE1 | |
| SCHEMBL17364128 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MAPTMEN1KMT2AEPHX2 | |
| SCHEMBL6663334 | 0.81 | ROCK2 (0.60) | MEN1KMT2AGAABACE1SMN1; SMN2 | |
| SCHEMBL10176502 | 0.81 | ROCK2 (0.60) | MEN1KMT2AGAABACE1SMN1; SMN2 | |
| SCHEMBL21880195 | 0.81 | ROCK2 (0.60) | MEN1KMT2AGAABACE1SMN1; SMN2 | |
| SCHEMBL29002157 | 0.81 | MAPK1 (0.63) | ALDH1A1MEN1KMT2ANPSR1BACE1 | |
| SCHEMBL28085751 | 0.81 | MAPK1 (0.63) | ALDH1A1MEN1KMT2ANPSR1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601734-B | Oximino naphthoquinone compound and preparation method and application thereof | 普济生物科技（台州）有限公司 | 2023-05-23 | — | — | CN | disclosed |