SCHEMBL30452475

SCHEMBL30452475

CC(C)=[Hf](C1C=CC=C1)C1c2cc(C(C)(C)C)ccc2-c2ccc(C(C)(C)C)cc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NPC1 O15118 1/20 0.32
PLA2G1B P04054 1/20 0.32
NFKB1 P19838 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ATG4B Q9Y4P1 1/20 0.32
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30451507 0.88 ALDH1A1 (0.33) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL30785854 0.86 NPC1 (0.32) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL20496057 0.85 HDAC1 (0.31) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL21270130 0.82 ALDH1A1 (0.34) ALDH1A1TDP1NPC1PLA2G1BNFKB1
SCHEMBL20496081 0.80 TRPV1 (0.35)
SCHEMBL30076488 0.79 ALDH1A1 (0.33) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL20972329 0.79 NR1H2 (0.30)
SCHEMBL29540602 0.79 NPC1 (0.34) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL19713482 0.77 NR1H2 (0.33)
SCHEMBL20496082 0.77 CES2 (0.39) ALDH1A1MEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250101156-A1 POLYOLEFIN COMPOSITIONS FEATURING IN SITU BLENDING OF AN OIL EXTENSION EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) 2025-03-27 US disclosed
US-12202920-B2 Olefin polymerization processes featuring in situ blending of an oil extension ExxonMobil Engineering & Technology Company (US) 2025-01-21 US disclosed
US-12006423-B2 Methods of making polymer compositions with enhanced elasticity by employing VTP and HMP catalyst systems in parallel processes ExxonMobil Engineering & Technology Company (US) 2024-06-11 US disclosed
EP-3841168-B1 METHODS OF MAKING POLYMER COMPOSITIONS WITH ENHANCED ELASTICITY BY EMPLOYING VTP AND HMP CATALYST SYSTEMS IN PARALLEL PROCESSES EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-01-17 EP disclosed
US-11708434-B2 Silica quenching agents for use in polymerization process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-07-25 US disclosed