SCHEMBL29540602

SCHEMBL29540602

CC(C)C(c1ccccc1)=[Hf](C1C=CC=C1)C1c2cc(C(C)(C)C)ccc2-c2ccc(C(C)(C)C)cc21

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34
PLA2G1B P04054 1/20 0.34
NFKB1 P19838 1/20 0.34
CASP3 P42574 1/20 0.34
RAB9A P51151 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29610200 0.89
SCHEMBL21270130 0.85 ALDH1A1 (0.34) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL30785854 0.82 NPC1 (0.32) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL21797763 0.79 KIF11 (0.33) ALDH1A1RAB9A
SCHEMBL29540998 0.79 KIF11 (0.33)
SCHEMBL30452475 0.79 ALDH1A1 (0.33) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL21797767 0.78 ALDH1A1 (0.33) ALDH1A1RAB9A
SCHEMBL20496057 0.78 HDAC1 (0.31) ALDH1A1
SCHEMBL32679461 0.76 NPC1 (0.33) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL29541627 0.76 CES2 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3555149-B1 NEW CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS BOREALIS GMBH (AT) 2025-11-12 EP claimed
US-11639399-B2 Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process BOREALIS AG (AT) 2023-05-02 US claimed
US-11530280-B2 Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process BOREALIS AG (AT) 2022-12-20 US claimed
US-20220325009-A1 NEW CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS BOREALIS AG (AT) 2022-10-13 US claimed
CN-110337455-B Catalyst system for the production of polyethylene copolymers in a high temperature solution polymerization process 博里利斯股份公司 2022-05-24 CN claimed
EP-3555149-B1 NEW CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS BOREALIS GMBH (AT) 2025-11-12 EP disclosed
US-11639399-B2 Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process BOREALIS AG (AT) 2023-05-02 US disclosed
EP-3555148-B1 CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS BOREALIS AG (AT) 2023-04-05 EP disclosed
US-11530280-B2 Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process BOREALIS AG (AT) 2022-12-20 US disclosed
US-20220325009-A1 NEW CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS BOREALIS AG (AT) 2022-10-13 US disclosed
CN-110337455-B Catalyst system for the production of polyethylene copolymers in a high temperature solution polymerization process 博里利斯股份公司 2022-05-24 CN disclosed
CN-110234665-B Catalyst system for preparing polyethylene copolymers in high temperature solution polymerization process 博里利斯股份公司 2022-05-24 CN disclosed
US-11279781-B2 Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process BOREALIS AG (AT) 2022-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11279781-B2 Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process OPRM1, SIGMAR1, AP2S1 NPC1 2435/4885ALDH1A1 4096/4885PLA2G1B 4065/4885
US-11639399-B2 Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process C1S, SIGMAR1, C1R NPC1 3202/4885ALDH1A1 4552/4885PLA2G1B 4056/4885
US-11530280-B2 Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process C1S, AP3S1, C5 NPC1 3247/4885ALDH1A1 4551/4885PLA2G1B 3981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.