Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29664619 | 1.00 | DRD2 (0.45) | DRD2DRD3DRD4PLAU | |
| SCHEMBL29664651 | 1.00 | DRD2 (0.45) | DRD2DRD3DRD4PLAU | |
| SCHEMBL21311659 | 0.79 | NISCH (0.39) | DRD2DRD3DRD4 | |
| SCHEMBL20095695 | 0.77 | CYP11B1 (0.41) | — | |
| SCHEMBL20095693 | 0.77 | CYP11B1 (0.41) | — | |
| SCHEMBL18493838 | 0.76 | DRD2 (0.45) | DRD2DRD3DRD4 | |
| SCHEMBL9684548 | 0.72 | DRD2 (0.56) | DRD2DRD3DRD4 | |
| SCHEMBL7815804 | 0.72 | NPC1 (0.45) | DRD2DRD3DRD4 | |
| SCHEMBL7803709 | 0.72 | NPC1 (0.45) | DRD2DRD3DRD4 | |
| Biphenyl SCHEMBL27474545 | 0.70 | ALDH1A1 (0.56) | DRD3PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111343990-B | Benzodiazepine-2-one and benzodiazepine-2-one derivatives | 英安塔制药有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-110809472-B | Process for preparing benzodiazepine derivatives | 英安塔制药有限公司 | 2023-05-23 | — | — | CN | disclosed |