Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 8/20 | 0.71 |
| ▸ | ATR | Q13535 | 2/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | GRK5 | P34947 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488314 | 1.00 | MET (0.71) | METATRMAP4K4JAK2FYN | |
| SCHEMBL488344 | 0.95 | MET (0.65) | METATRMAP4K4JAK2FYN | |
| SCHEMBL30453431 | 0.95 | MET (0.65) | METATRMAP4K4JAK2FYN | |
| SCHEMBL488067 | 0.93 | MET (0.62) | METMAP4K4ERN1ADORA2AADORA2B | |
| SCHEMBL30453726 | 0.93 | MET (0.62) | METMAP4K4ERN1ADORA2AADORA2B | |
| SCHEMBL30452893 | 0.93 | MET (0.81) | METATRJAK2 | |
| SCHEMBL488700 | 0.93 | MET (0.81) | METATRJAK2 | |
| SCHEMBL488308 | 0.92 | MET (0.61) | METATRMAP4K4JAK2FYN | |
| SCHEMBL487752 | 0.92 | MET (0.85) | METJAK2ALK | |
| SCHEMBL30453645 | 0.92 | MET (0.85) | METJAK2ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |