Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.62 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.52 |
| ▸ | GRK5 | P34947 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488067 | 1.00 | MET (0.62) | METALKGRK5MAP4K4PIK3CD | |
| SCHEMBL30452523 | 0.93 | MET (0.71) | METALKCD274 | |
| SCHEMBL488275 | 0.93 | MET (0.71) | METALKCD274 | |
| SCHEMBL30452645 | 0.93 | MET (0.71) | METALKGRK5MAP4K4ERN1 | |
| SCHEMBL488314 | 0.93 | MET (0.71) | METALKGRK5MAP4K4ERN1 | |
| SCHEMBL30453721 | 0.92 | MET (0.75) | METALK | |
| SCHEMBL487746 | 0.92 | MET (0.75) | METALK | |
| SCHEMBL488589 | 0.90 | MET (0.68) | METALKGRK5MAP4K4 | |
| SCHEMBL30453756 | 0.90 | MET (0.68) | METALKGRK5MAP4K4 | |
| SCHEMBL488308 | 0.90 | MET (0.61) | METALKGRK5MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |