Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.61 |
| ▸ | MAP4K3 | Q8IVH8 | 3/20 | 0.43 |
| ▸ | USP7 | Q93009 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487923 | 1.00 | MET (0.61) | METMAP4K3USP7CNR2JAK2 | |
| SCHEMBL487806 | 0.85 | MET (0.60) | METMAP4K3USP7JAK2ALOX5AP | |
| SCHEMBL30454267 | 0.85 | MET (0.60) | METMAP4K3USP7JAK2ALOX5AP | |
| SCHEMBL30453367 | 0.85 | MET (0.65) | METMAP4K3USP7JAK2MAP4K4 | |
| SCHEMBL487729 | 0.85 | MET (0.65) | METMAP4K3USP7JAK2MAP4K4 | |
| SCHEMBL6361398 | 0.83 | MET (0.69) | METMAP4K3USP7CNR2JAK2 | |
| SCHEMBL30452575 | 0.82 | MET (0.72) | METMAP4K3USP7JAK2ALOX5AP | |
| SCHEMBL487522 | 0.82 | MET (0.72) | METMAP4K3USP7JAK2ALOX5AP | |
| SCHEMBL487708 | 0.81 | MET (0.74) | METMAP4K3JAK2MAP4K4MPO | |
| SCHEMBL488125 | 0.81 | MET (0.63) | METMAP4K3USP7MAP4K4PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |