Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.60 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487806 | 1.00 | MET (0.60) | METALOX5APFEN1SCN9APTGER1 | |
| SCHEMBL487923 | 0.85 | MET (0.61) | METALOX5APFEN1SCN9APTGER1 | |
| SCHEMBL30452662 | 0.85 | MET (0.61) | METALOX5APFEN1SCN9APTGER1 | |
| SCHEMBL488125 | 0.85 | MET (0.63) | METPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL30453937 | 0.85 | MET (0.63) | METPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL487962 | 0.84 | MET (0.62) | METFEN1PTGER1PTGER4PTGER3 | |
| SCHEMBL30453367 | 0.84 | MET (0.65) | METPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL487729 | 0.84 | MET (0.65) | METPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL487821 | 0.83 | MET (0.61) | METPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL488173 | 0.82 | MET (0.63) | METMAP4K3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |