Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.54 |
| ▸ | JAK2 | O60674 | 2/20 | 0.53 |
| ▸ | MET | P08581 | 2/20 | 0.52 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488416 | 1.00 | MAP4K3 (0.54) | MAP4K3JAK2METSGMS2MPO | |
| SCHEMBL488082 | 0.89 | MET (0.61) | MAP4K3JAK2METMPOMAP4K4 | |
| SCHEMBL488108 | 0.88 | MAP4K3 (0.56) | MAP4K3JAK2METMPOMAP4K4 | |
| SCHEMBL488667 | 0.86 | MET (0.70) | MAP4K3JAK2METSGMS2MPO | |
| SCHEMBL30452701 | 0.86 | MET (0.70) | MAP4K3JAK2METSGMS2MPO | |
| SCHEMBL488210 | 0.85 | MET (0.57) | MAP4K3METMPOMAP4K4INPPL1 | |
| SCHEMBL30453912 | 0.85 | MET (0.57) | MAP4K3METMPOMAP4K4INPPL1 | |
| SCHEMBL487657 | 0.82 | MET (0.75) | MAP4K3METMPOMAPTMAP4K4 | |
| SCHEMBL30452824 | 0.82 | MET (0.75) | MAP4K3METMPOMAPTMAP4K4 | |
| SCHEMBL27630242 | 0.82 | MET (0.75) | MAP4K3METMPOMAPTMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |