Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16794599 | 1.00 | TYK2 (0.36) | TYK2MAPTKDM4EMEN1TDP2 | |
| SCHEMBL29868212 | 0.81 | ALDH1A1 (0.43) | TYK2MAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL23327205 | 0.81 | ALDH1A1 (0.43) | TYK2MAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL20688028 | 0.78 | TYK2 (0.50) | TYK2MAPT | |
| SCHEMBL29903145 | 0.77 | RECQL (0.46) | KDM4EALDH1A1 | |
| SCHEMBL16812415 | 0.77 | RECQL (0.46) | KDM4EALDH1A1 | |
| SCHEMBL20689571 | 0.77 | TYK2 (0.50) | TYK2MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL23753623 | 0.76 | NOS3 (0.39) | TYK2ALDH1A1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL16812404 | 0.76 | AURKA (0.33) | — | |
| SCHEMBL16812345 | 0.76 | GABRA5 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916207-A | Five-membered and six-membered heterocyclic compounds and application thereof as protein receptor kinase inhibitors | 轶诺(浙江)药业有限公司 | 2023-04-04 | — | — | CN | disclosed |