Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.55 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.55 |
| ▸ | ATR | Q13535 | 4/20 | 0.53 |
| ▸ | SMYD2 | Q9NRG4 | 4/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488699 | 1.00 | MET (0.55) | METCHEK2ATRSMYD2MAP4K4 | |
| SCHEMBL488359 | 0.95 | ATR (0.59) | METCHEK2ATRMAP4K4IKBKB | |
| SCHEMBL30453791 | 0.95 | ATR (0.59) | METCHEK2ATRMAP4K4IKBKB | |
| SCHEMBL487993 | 0.93 | MET (0.63) | METCHEK2ATRDRD2 | |
| SCHEMBL30453082 | 0.93 | MET (0.63) | METCHEK2ATRDRD2 | |
| SCHEMBL488485 | 0.92 | MET (0.62) | METCHEK2ATRSMYD2MAP4K4 | |
| SCHEMBL30453330 | 0.92 | MET (0.62) | METCHEK2ATRSMYD2MAP4K4 | |
| SCHEMBL488299 | 0.90 | MET (0.56) | METCHEK2ATRSMYD2MAP4K4 | |
| SCHEMBL30452920 | 0.90 | MET (0.56) | METCHEK2ATRSMYD2MAP4K4 | |
| SCHEMBL27650159 | 0.89 | ATR (0.50) | METCHEK2ATRSMYD2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |