Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.63 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.63 |
| ▸ | ATR | Q13535 | 6/20 | 0.51 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487993 | 1.00 | MET (0.63) | METCHEK2ATRCSF1RHTR1A | |
| SCHEMBL30453897 | 0.95 | MET (0.65) | METCHEK2ATRCSF1R | |
| SCHEMBL488319 | 0.95 | MET (0.65) | METCHEK2ATRCSF1R | |
| SCHEMBL30452733 | 0.93 | MET (0.55) | METCHEK2ATRDRD2 | |
| SCHEMBL488699 | 0.93 | MET (0.55) | METCHEK2ATRDRD2 | |
| SCHEMBL488473 | 0.89 | MET (0.62) | METCHEK2ATRLMNAMAPT | |
| SCHEMBL30452643 | 0.89 | MET (0.62) | METCHEK2ATRLMNAMAPT | |
| SCHEMBL488149 | 0.88 | MET (0.60) | METCHEK2ATRHTR1A | |
| SCHEMBL30454540 | 0.88 | MET (0.60) | METCHEK2ATRHTR1A | |
| SCHEMBL30453791 | 0.88 | ATR (0.59) | METCHEK2ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |