Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257771 | 1.00 | GRM5 (0.42) | GRM5CNR1SQORFNTAFNTB | |
| SCHEMBL24257768 | 0.89 | SQOR (0.42) | CNR1SQORADORA2AADORA1GABRG2 | |
| SCHEMBL30546869 | 0.87 | C5AR1 (0.41) | SQORADORA2AADORA1GABRG2GABRB3 | |
| SCHEMBL24257769 | 0.87 | C5AR1 (0.41) | SQORADORA2AADORA1GABRG2GABRB3 | |
| SCHEMBL24257562 | 0.86 | MAOB (0.47) | SQORADORA2AADORA1HPGDCYP2C9 | |
| SCHEMBL30546831 | 0.86 | MAOB (0.47) | SQORADORA2AADORA1HPGDCYP2C9 | |
| SCHEMBL24257522 | 0.86 | SQOR (0.40) | SQORGABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30452556 | 0.84 | CNR1 (0.40) | GRM5CNR1SQORFNTAFNTB | |
| SCHEMBL24257707 | 0.84 | CNR1 (0.40) | GRM5CNR1SQORFNTAFNTB | |
| SCHEMBL24257819 | 0.83 | HSD17B10 (0.43) | CNR1SQORADORA2AADORA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670131-A | PHD inhibitor compounds, compositions, and methods of use | 阿克比治疗有限公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-4196466-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Akebia Therapeutics Inc. (US) | 2023-06-21 | — | — | EP | disclosed |