Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.55 |
| ▸ | FYN | P06241 | 3/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.48 |
| ▸ | USP7 | Q93009 | 2/20 | 0.47 |
| ▸ | XDH | P47989 | 2/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488223 | 1.00 | MET (0.56) | METMAP4K4FYNTGFBR1USP7 | |
| SCHEMBL30453341 | 0.87 | MAP4K4 (0.75) | METMAP4K4XDHRAB9AL3MBTL1 | |
| SCHEMBL488616 | 0.87 | MAP4K4 (0.75) | METMAP4K4XDHRAB9AL3MBTL1 | |
| SCHEMBL27650357 | 0.87 | MET (0.51) | METMAP4K4FYNXDHMAP4K3 | |
| SCHEMBL6416738 | 0.83 | MAP4K4 (0.48) | METMAP4K4FYNXDHMAP4K3 | |
| SCHEMBL30452754 | 0.83 | MAP4K4 (0.76) | METMAP4K4FYNTGFBR1USP7 | |
| SCHEMBL487854 | 0.83 | MAP4K4 (0.76) | METMAP4K4FYNTGFBR1USP7 | |
| SCHEMBL27650167 | 0.81 | MET (0.59) | METMAP4K4XDHMAP4K3ALOX5AP | |
| SCHEMBL10381732 | 0.80 | MET (0.44) | METMAP4K4XDHMAP4K3RAB9A | |
| SCHEMBL488365 | 0.80 | MET (0.65) | METMAP4K4TGFBR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |