SCHEMBL30452755

SCHEMBL30452755

Cc1cc(Nc2cc(C)[nH]n2)nc(N2CCC(C)(NC(=O)OC(C)(C)C)CC2)n1

nearest known ligand 0.56

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RET P07949 20/20 0.56
JAK2 O60674 1/20 0.40
FLT3 P36888 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28429868 1.00 RET (0.56) RETJAK2FLT3
SCHEMBL30453004 0.86 RET (0.61) RETJAK2FLT3
SCHEMBL29016163 0.86 RET (0.61) RETJAK2FLT3
SCHEMBL30453270 0.84 RET (0.61) RETJAK2
SCHEMBL30452041 0.82 RET (0.56) RET
SCHEMBL28433635 0.82 RET (0.56) RET
SCHEMBL21744548 0.82 RET (0.54) RETJAK2
SCHEMBL10060060 0.79 RET (0.56) RET
SCHEMBL19796299 0.78 RET (0.73) RET
Hydrochloric Acid SCHEMBL30453172 0.77 RET (0.59) RETJAK2FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108676-B Benzenesulfonamide compound, pharmaceutical composition and application thereof 中国药科大学 2025-02-07 CN disclosed
CN-118108676-A Benzenesulfonamide compound, pharmaceutical composition and application thereof 中国药科大学 2024-05-31 CN disclosed
CN-114096532-B Heterocyclic compounds which inhibit tyrosine kinase 2 activity 广州诺诚健华医药科技有限公司 2023-12-01 CN disclosed
CN-116507326-A Compounds as GLP-1R agonists 拓臻制药公司 2023-07-28 CN disclosed
CN-111484479-B Azacyclic compounds, pharmaceutical compositions containing the same, and methods of making and using the same 四川科伦博泰生物医药股份有限公司 2023-06-13 CN disclosed