Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 8/20 | 0.54 |
| ▸ | MERTK | Q12866 | 8/20 | 0.43 |
| ▸ | AXL | P30530 | 6/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.36 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488368 | 1.00 | MET (0.54) | METMERTKAXLATRALK | |
| SCHEMBL488369 | 0.85 | MET (0.55) | METMERTKAXLATRBMPR1B | |
| SCHEMBL30452853 | 0.84 | MET (0.61) | METMERTKAXLATR | |
| SCHEMBL488874 | 0.84 | MET (0.61) | METMERTKAXLATR | |
| SCHEMBL30453810 | 0.84 | MET (0.55) | METMERTKAXLATRL3MBTL3 | |
| SCHEMBL487976 | 0.84 | MET (0.55) | METMERTKAXLATRL3MBTL3 | |
| SCHEMBL5255609 | 0.78 | MET (0.70) | METMERTKAXLATRL3MBTL3 | |
| SCHEMBL488661 | 0.78 | MET (0.65) | METMERTKAXLATRL3MBTL3 | |
| SCHEMBL30453983 | 0.78 | MET (0.65) | METMERTKAXLATRL3MBTL3 | |
| SCHEMBL30453313 | 0.77 | MET (0.56) | METMERTKAXLATRL3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |