Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 7/20 | 0.51 |
| ▸ | CSF1R | P07333 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487837 | 1.00 | LMNA (0.53) | LMNAHTTMAP4K4FYNCSF1R | |
| SCHEMBL30453441 | 0.81 | MAP4K3 (0.60) | HTTMAP4K4FYNSMN1; SMN2MET | |
| SCHEMBL487975 | 0.81 | MAP4K3 (0.60) | HTTMAP4K4FYNSMN1; SMN2MET | |
| SCHEMBL488178 | 0.80 | MAP4K4 (0.75) | MAP4K4FYNMETJAK2 | |
| SCHEMBL488734 | 0.78 | NPC1 (0.61) | MAP4K4FYNALDH1A1METJAK2 | |
| SCHEMBL30453760 | 0.78 | NPC1 (0.61) | MAP4K4FYNALDH1A1METJAK2 | |
| SCHEMBL487796 | 0.77 | MET (0.57) | MAP4K4FYNMETJAK2MAPT | |
| Water SCHEMBL28122580 | 0.76 | MET (0.56) | MAP4K4FYNMETJAK2MAPT | |
| SCHEMBL487622 | 0.75 | MET (0.52) | MAP4K4FYNMETJAK2MAPT | |
| SCHEMBL15338674 | 0.75 | MAP4K4 (0.60) | MAP4K4FYNMETJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |