Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.60 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 5/20 | 0.54 |
| ▸ | FYN | P06241 | 5/20 | 0.52 |
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487975 | 1.00 | MAP4K3 (0.60) | MAP4K3MAP4K4MAOBFYNHTR1A | |
| SCHEMBL488178 | 0.85 | MAP4K4 (0.75) | MAP4K3MAP4K4MAOBFYNMET | |
| SCHEMBL15338674 | 0.82 | MAP4K4 (0.60) | MAP4K3MAP4K4FYNIDO1AGXT | |
| SCHEMBL487837 | 0.81 | LMNA (0.53) | MAP4K4FYNMAPTHTTSMN1; SMN2 | |
| SCHEMBL30452867 | 0.81 | LMNA (0.53) | MAP4K4FYNMAPTHTTSMN1; SMN2 | |
| SCHEMBL29870411 | 0.80 | NPC1 (0.55) | MAP4K4MAOBHTR1ADRD2ABCB1 | |
| SCHEMBL28513683 | 0.80 | NPC1 (0.55) | MAP4K4MAOBHTR1ADRD2ABCB1 | |
| SCHEMBL10214982 | 0.78 | MAOB (0.46) | MAP4K3MAOBHTR1ADRD2ABCB1 | |
| SCHEMBL30454973 | 0.78 | MET (0.67) | MAP4K3MAP4K4FYNMAPTSMN1; SMN2 | |
| SCHEMBL488061 | 0.78 | MET (0.67) | MAP4K3MAP4K4FYNMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |