Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 8/20 | 0.53 |
| ▸ | JAK2 | O60674 | 5/20 | 0.49 |
| ▸ | JAK1 | P23458 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.49 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.48 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 3/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487738 | 1.00 | MET (0.53) | METJAK2JAK1TYK2JAK3 | |
| SCHEMBL5480975 | 0.85 | MET (0.53) | METJAK2MAP4K3ALK | |
| SCHEMBL487679 | 0.82 | MET (0.57) | METJAK2MAP4K3ALK | |
| SCHEMBL27630082 | 0.79 | FYN (0.50) | METJAK2MAP4K3ALK | |
| SCHEMBL27650146 | 0.78 | MET (0.60) | METJAK2MAP4K3 | |
| SCHEMBL5482786 | 0.78 | MET (0.50) | METJAK2MAP4K3AXLALK | |
| SCHEMBL30453168 | 0.78 | JAK2 (0.60) | METJAK2MAP4K3 | |
| SCHEMBL487842 | 0.78 | JAK2 (0.60) | METJAK2MAP4K3 | |
| SCHEMBL488121 | 0.78 | MAP4K4 (0.54) | METJAK2MAP4K3 | |
| SCHEMBL30453459 | 0.78 | MAP4K4 (0.54) | METJAK2MAP4K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |