Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.60 |
| ▸ | MET | P08581 | 9/20 | 0.50 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487842 | 1.00 | JAK2 (0.60) | JAK2METMAP4K3MKNK1MKNK2 | |
| SCHEMBL487679 | 0.88 | MET (0.57) | JAK2METMAP4K3FYN | |
| SCHEMBL488295 | 0.87 | MET (0.52) | JAK2METMAP4K3 | |
| SCHEMBL30452799 | 0.87 | MET (0.52) | JAK2METMAP4K3 | |
| SCHEMBL488590 | 0.87 | JAK2 (0.51) | JAK2METMAP4K3 | |
| SCHEMBL5480975 | 0.85 | MET (0.53) | JAK2METMAP4K3FYN | |
| SCHEMBL28515206 | 0.85 | JAK2 (0.62) | JAK2METMAP4K3MKNK1MKNK2 | |
| SCHEMBL488147 | 0.85 | MET (0.52) | JAK2METMAP4K3 | |
| SCHEMBL30453038 | 0.85 | MET (0.52) | JAK2METMAP4K3 | |
| SCHEMBL488667 | 0.83 | MET (0.70) | JAK2METMAP4K3MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |