Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATR | Q13535 | 2/20 | 0.45 |
| ▸ | GRK5 | P34947 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488205 | 1.00 | MAP4K4 (0.49) | MAP4K4KLK7KMT2AATRGRK5 | |
| SCHEMBL488692 | 0.96 | MAP4K4 (0.54) | MAP4K4ATRGRK5ALDH1A1PIK3CD | |
| SCHEMBL30453395 | 0.96 | MAP4K4 (0.54) | MAP4K4ATRGRK5ALDH1A1PIK3CD | |
| SCHEMBL488105 | 0.93 | ATR (0.53) | MAP4K4KMT2AATR | |
| SCHEMBL30453359 | 0.93 | ATR (0.53) | MAP4K4KMT2AATR | |
| SCHEMBL488475 | 0.92 | KLK7 (0.47) | KLK7KMT2AALDH1A1 | |
| SCHEMBL30454451 | 0.92 | KLK7 (0.47) | KLK7KMT2AALDH1A1 | |
| SCHEMBL488217 | 0.89 | ATR (0.58) | MAP4K4ATR | |
| SCHEMBL30454379 | 0.89 | ATR (0.58) | MAP4K4ATR | |
| SCHEMBL30453447 | 0.88 | MET (0.49) | MAP4K4KLK7KMT2AGRK5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |