Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 5/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | SMYD2 | Q9NRG4 | 6/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488105 | 1.00 | ATR (0.53) | ATRMAP4K4SMYD2CSF1RMET | |
| SCHEMBL488217 | 0.95 | ATR (0.58) | ATRMAP4K4CSF1RMETIKBKB | |
| SCHEMBL30454379 | 0.95 | ATR (0.58) | ATRMAP4K4CSF1RMETIKBKB | |
| SCHEMBL488205 | 0.93 | MAP4K4 (0.49) | ATRMAP4K4KMT2A | |
| SCHEMBL30452963 | 0.93 | MAP4K4 (0.49) | ATRMAP4K4KMT2A | |
| SCHEMBL488513 | 0.92 | ATR (0.50) | ATRCSF1RMETMAPTMEN1 | |
| SCHEMBL30453094 | 0.92 | ATR (0.50) | ATRCSF1RMETMAPTMEN1 | |
| SCHEMBL5488293 | 0.90 | ATR (0.50) | ATRMAP4K4SMYD2CSF1RMET | |
| SCHEMBL30453395 | 0.89 | MAP4K4 (0.54) | ATRMAP4K4 | |
| SCHEMBL488692 | 0.89 | MAP4K4 (0.54) | ATRMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |